Anti-Human HPSE Recombinant Antibody (22D9)
CAT#: TAB-280CQ
This antibody likely binds to the small subunit or a site on the large subunit that is in close proximity to the small subunit and significantly inhibits cell motility.
Published Data
Gene Expression
FuncS
Figure 1 is a graph showing the effect of human monoclonal antibody 22D9 on the growth of MDA-MB 435 cells in nu/nu mice.
Inhib
Figure 2 is a graph showing comparable inhibition of heparanase activity with human monoclonal antibody 22D9 at pH5.2 and 7.4.
Inhib
Figure 3 is a graph showing that human monoclonal antibody 22D9 inhibits heparanase activity in a dose dependent manner at pH5.2.
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55344/874_A7_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & Vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55344/886_H3_2_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55344/881_A7_1_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707, OE19, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173083-HPSE
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Specifications
- Immunogen
- Recombinant heparanase
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 22D9
- Applications
- FuncS, Inhib
- Related Disease
- Asthma, lupus erythematosus and allograft rejection
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay, Inhibition.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 22D9"
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- Product Name
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Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-673-sdAb | Recombinant Anti-human HPSE VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-025CT | Anti-Human Heparanase Recombinant Antibody (10E9.1) | ELISA, Inhibition, FC | Human antibody |
| TAB-025CT-S(P) | Anti-Human Heparanase Recombinant Antibody scFv Fragment (10E9.1) | ELISA, Inhibition, FC | Human antibody |
| TAB-025CT-F(E) | Anti-Human Heparanase Recombinant Antibody Fab Fragment (10E9.1) | ELISA, Inhibition, FC | Human antibody |
| TAB-280CQ-S(P) | Anti-Human HPSE Recombinant Antibody scFv Fragment (22D9) | ELISA, FC, WB | Human antibody |
| TAB-280CQ-F(E) | Anti-Human HPSE Recombinant Antibody Fab Fragment (22D9) | ELISA, FC, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0628CT | Recombinant Mouse anti-Human HPSE Monoclonal antibody (EML1141) | WB | |
| HPAB-0265-YC | Mouse Anti-HPSE Recombinant Antibody (HPAB-0265-YC) | FC, Neut, FuncS | Mouse IgG |
| VS13-YC549 | Rabbit Anti-HPSE Recombinant Antibody (VS13-YC549) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1672 | Rabbit Anti-HPSE Recombinant Antibody (clone DS1672AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0264-YC | Mouse Anti-HPSE Recombinant Antibody (HPAB-0264-YC) | WB, IF | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0264-YC-S(P) | Mouse Anti-HPSE Recombinant Antibody; scFv Fragment (HPAB-0264-YC-S(P)) | FC, Neut, FuncS | Mouse scFv |
| HPAB-0265-YC-S(P) | Mouse Anti-HPSE Recombinant Antibody; scFv Fragment (HPAB-0265-YC-S(P)) | FC, Neut, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0264-YC-F(E) | Mouse Anti-HPSE Recombinant Antibody; Fab Fragment (HPAB-0264-YC-F(E)) | FC, Neut, FuncS | Mouse Fab |
| HPAB-0265-YC-F(E) | Mouse Anti-HPSE Recombinant Antibody; Fab Fragment (HPAB-0265-YC-F(E)) | FC, Neut, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0853 | PE-A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer | FCM, IHC | |
| MHC-CN0854 | APC-A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer | FCM, IHC | |
| MHC-CN0855 | FITC-A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer | FCM, IHC | |
| MHC-YF472 | A*02:01/Human Heparanase (ALPPPLMLL) MHC Pentamer | FCM | |
| MHC-YF473 | A*02:01/Human Heparanase (DLIFGLNAL) MHC Pentamer | FCM |
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