Anti-HTNV G2 Recombinant Antibody (11E10)
CAT#: MRO-1077LC
This product is a recombinant mouse anti-Hantaan Virus monoclonal antibody. 11E10 specifically binds to G2 protein associated with HTNV and can be potentially used in the treatment and diagnosis of Hantaan Virus infection.
Published Data
IP
Figure 1 SDS-PAGE of affinity-purified recombinant human IgG antibodies to HTNV.
Radiolabeled HTNV proteins were immunoprecipitated with HFRS patient serum (lane HP) or with recombinant human antibodies as indicated above each lane. The positions of the viral envelope glycoproteins, G1 and G2, and the nucleocapsid protein, N, are indicated to the left of the autoradiogram.
Generation of an HFRS Patient-Derived Neutralizing Recombinant Antibody to Hantaan Virus G1 Protein and Definition of the Neutralizing Domain
ELISA
Figure 2 Competitive inhibition ELISA with biotin-labelled MAb I1Et0 and competing MAbs llEI0 (O), HCO2 (0) and 8E 10 (D).
Competition of individual MAbs with each of the other MAbs revealed three different competitive inhibition binding curves. In this example, 10-fold dilutions of unlabelled MAbs HCO2, 8E 10 and 11E 10 were added to antigen-coated wells, Competition with MAb 11E 10 was assessed by the addition of biotin-labelled 11E10 as described in Methods. Bound, biotinqabelled antibody was measured as described in the text. MAbs 11E10, HCO2 and 8El0 showed inhibition, no inhibition and + inhibition, respectively.
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Specifications
- Host Species
- Mouse
- Type
- Mouse Antibody
- Specificity
- Hantaan Virus
- Clone
- 11E10
- Applications
- ELISA, IP
- Related Disease
- Hantaan Virus infection
Applications
- Application Notes
- The HTNV G2 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunoprecipitation.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Clone 11E10"
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See other products for "HTNV G2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1076LC-F(E) | Anti-HTNV G2 Recombinant Antibody Fab Fragment (16E6) | ELISA | Mouse Antibody |
| MRO-1077LC-F(E) | Anti-HTNV G2 Recombinant Antibody Fab Fragment (11E10) | ELISA | Mouse Antibody |
| MRO-1078LC-F(E) | Anti-HTNV G2 Recombinant Antibody Fab Fragment (17G6) | ELISA | Mouse Antibody |
| MRO-1079LC-F(E) | Anti-HTNV G2 Recombinant Antibody Fab Fragment (3D7) | ELISA | Mouse Antibody |
| MRO-1080LC-F(E) | Anti-HTNV G2 Recombinant Antibody Fab Fragment (5B7) | ELISA | Mouse Antibody |
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