Recombinant Mouse anti-Human MCM7 Monoclonal antibody (EDT-252)
CAT#: MOB-1147CT
Recombinant Mouse monoclonal antibody to Human MCM7, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3898/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2163/if_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/if_selected.jpg
Normal Tissue
Figure 4 Tonsil
High expression in tonsil
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3898/10901_A_5_8_selected.jpg
Normal Tissue
Figure 5 Bone marrow
High expression in bone marrow
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_B_5_4_val_selected.jpg
Normal Tissue
Figure 6 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Mucosal lymphoid cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_A_8_3.jpg
Normal Tissue
Figure 7 Kidney
Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_A_9_5.jpg
Normal Tissue
Figure 8 Skin
Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: Medium Intensity: Strong Quantity: <25% Endothelial cells Staining: High Intensity: Strong Fibrohistiocytic cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_B_7_1.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166508-MCM7
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Specifications
- Immunogen
- Recombinant full length MCM7 (Human)
- Host Species
- Mouse
- Specificity
- Recognizes human Mcm7 and also a weaker lower molecular weight doublet.
- Species Reactivity
- Human
- Clone
- EDT-252
- Applications
- Used for immunoassay techniques such as: Immunocytochemistry/Immunofluorescence; Immunoprecipitation; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Ascites
- Format
- Liquid
- Concentration
- 10.0 mg/ml
- Buffer
- Preservative: 15mM Sodium Azide Constituents: Ascites
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- MCM7; minichromosome maintenance complex component 7; MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3; DNA replication licensing factor MCM7; CDC47 homolog; homolog of S. cerevisiae Cdc47; minichromosome maintenance deficient 7; protein phosphatase 1, regulatory subunit 104;
- Gene ID
- 4176
- UniProt ID
- P33993
- Protein Refseq
- NP_005907
- Function
- ATP binding; contributes_to ATP-dependent DNA helicase activity; contributes_to DNA binding; hydrolase activity; nucleotide binding; protein binding; single-stranded DNA binding;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "MCM7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0743CL | Mouse Anti-MCM7 Recombinant Antibody (TAB-0743CL) | ELISA | Mouse IgG1 |
| TAB-0743CL-S(P) | Mouse Anti-MCM7 Recombinant Antibody; scFv Fragment (TAB-0743CL-S(P)) | ELISA | Mouse scFv |
| TAB-0743CL-F(E) | Mouse Anti-MCM7 Recombinant Antibody; Fab Fragment (TAB-0743CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2194 | Hi-Affi™ Recombinant Rabbit Anti-MCM7 Monoclonal Antibody (DS2194AB) | ICC, IF, WB, IP, ICC, FC, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY913 | Recombinant Rabbit Anti-MCM7 Antibody (clone R07-7A4) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1324 | Anti-MCM7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4314 | Anti-Human MCM7 Immunohistochemistry Kit | IHC |
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