Recombinant Mouse anti-Human NTHL1 Monoclonal antibody (FQ806Z)

Name: Recombinant Mouse anti-Human NTHL1 Monoclonal antibody (FQ806Z)
SKU: MOB-2306CT
Rating: 5 (1 reviews)

CAT#: MOB-2306CT

Recombinant Mouse Monoclonall antibody to Human NTHL1, expressed in Chinese Hamster Ovary cells(CHO).

Gene Expression

Normal Tissue Figure 1 Cerebral cortex

Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_B_8_5.jpg

Normal Tissue Figure 2 Colon

Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_A_7_3.jpg

Normal Tissue Figure 3 Liver

Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_A_7_4.jpg

Normal Tissue Figure 4 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_A_8_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Peritubular cells Staining: Low Intensity: Moderate Quantity: <25% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Strong Quantity: <25% Spermatogonia cells Staining: Medium Intensity: Moderate

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_A_5_6.jpg

Normal Tissue Figure 6 Heart muscle

Cardiomyocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_B_6_6.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25152/54560_A_9_8.jpg

RNA Expression Figure 8 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000065057-NTHL1

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Specifications

Immunogen
Recombinant N-terminal fragment of human NTH1

Host Species
Mouse

Specificity
Widely expressed with highest levels in heart and lowest levels in lung and liver.

Species Reactivity
Human

Clone
FQ806Z

Applications
Used for immunoassay techniques such as: Western Blot; Dot blot

Conjugate
Unconjugated

Product Property

Purity
Protein G purified

Format
Liquid

Buffer
Preservative: 0.05% Sodium Azide. Constituents: 1% BSA, PBS, pH 7.4

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Alternative Names
NTHL1; nth endonuclease III-like 1 (E. coli); NTH1; OCTS3; hNTH1; endonuclease III-like protein 1; DNA glycoslyase/AP lyase; bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase;

Gene ID
4913

UniProt ID
P78549

Protein Refseq
NP_002519

Function
4 iron, 4 sulfur cluster binding; DNA N-glycosylase activity; DNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; double-stranded DNA binding; endonuclease activity; hydrolase activity, acting on glycosyl bonds; lyase activity; metal ion bind

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-2306CT.pdf

MSDS

MSDS - MOB-2306CT.pdf

COA

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VS4-CJ61	Recombinant Rabbit Anti-NTHL1 Antibody (clone 22H10)	ELISA, WB, IHC, IF, FC	Rabbit IgG
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CAT	Product Name	Application	Type
VS-0525-XY5010	Anti-NTHL1 Immunohistochemistry Kit	IHC

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