Recombinant Mouse anti-Human PDCD4 Monoclonal antibody (L5D2)
CAT#: MOB-1301CT
Recombinant Mouse monoclonal antibody to Human PDCD4, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27214/231_F5_2_selected.jpg
Normal Tissue
Figure 2 Pancreas
High expression in pancreas
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_2_3_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human thyroid gland
Immunohistochemical staining of human thyroid gland shows strong nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37024/78562_B_3_5_selected.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: Medium Intensity: Strong Quantity: <25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Round or early spermatids Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_6_6.jpg
Normal Tissue
Figure 5 Lymph node
Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_8.jpg
Normal Tissue
Figure 6 Cerebral cortex
Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_B_8_5.jpg
Normal Tissue
Figure 7 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_3.jpg
Normal Tissue
Figure 8 Kidney
Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_5.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (T-47d, U-266/70)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000150593-PDCD4
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Specifications
- Immunogen
- Full-length human PDCD4 (amino acids 1-469), recombinantly produced and purified from E. coli.
- Host Species
- Mouse
- Antibody Isotype
- IgG1
- Species Reactivity
- Human
- Clone
- L5D2
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 0.1 mg/ml
- Buffer
- pH: 7.40Preservative:0.1% Sodium azideConstituent:99% PBS
- Storage
- Store at +4°C or -20°C long term. Avoid repeated freeze / thaw cycles. Store undiluted.
Target
- Alternative Names
- PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); H731; programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein;
- Gene ID
- 27250
- UniProt ID
- Q53EL6
- Protein Refseq
- NP_001186421
- Function
- RNA binding; binding; protein binding;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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