Recombinant Mouse anti-Human PDCD4 Monoclonal antibody (L5D2) (CAT#: MOB-1301CT)
Recombinant Mouse monoclonal antibody to Human PDCD4, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27214/231_F5_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27214/231_F5_2_selected.jpg
Figure 2 Pancreas
(High expression in pancreas)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_2_3_val_selected.jpg
(High expression in pancreas)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_2_3_val_selected.jpg
Figure 3 IHC staining of human thyroid gland
(Immunohistochemical staining of human thyroid gland shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37024/78562_B_3_5_selected.jpg
(Immunohistochemical staining of human thyroid gland shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37024/78562_B_3_5_selected.jpg
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: Medium Intensity: Strong Quantity: <25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Round or early spermatids Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: Medium Intensity: Strong Quantity: <25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Round or early spermatids Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_6_6.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_8.jpg
Figure 6 Cerebral cortex
(Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_B_8_5.jpg
(Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_B_8_5.jpg
Figure 7 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_3.jpg
Figure 8 Kidney
(Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_5.jpg
(Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1032/2348_A_7_5.jpg
Figure 9 RNA cell line category: Cell line enhanced (T-47d, U-266/70)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000150593-PDCD4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000150593-PDCD4
Specifications
- Immunogen
- Recombinant full length protein, corresponding to amino acids 1-469 of Human PDCD4, purified from E. coli.
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- L5D2
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 0.1 mg/ml
- Buffer
- pH: 7.40Preservative:0.1% Sodium azideConstituent:99% PBS
- Storage
- Store at +4°C or -20°C long term. Avoid repeated freeze / thaw cycles. Store undiluted.
Target
- Alternative Names
- PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); H731; programmed cell death protein 4; protein 197/15a; nuclear antigen H731; neoplastic transformation inhibitor protein;
- Gene ID
- 27250
- UniProt ID
- Q53EL6
- Protein Refseq
- NP_001186421
- Function
- RNA binding; binding; protein binding;
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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