Recombinant Mouse anti-Human PITX1 Monoclonal antibody (EML621) (CAT#: MOB-0180CT)
Recombinant Mouse monoclonal antibody to Human PITX1, expressed in Chinese Hamster Ovary cells(CHO).
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/if_selected.jpg
Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_B_4_1_selected.jpg
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_B_4_1_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/110_G6_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/110_G6_1_blue_red_green.jpg
Figure 4 Esophagus
(Squamous epithelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_B_4_1.jpg
(Squamous epithelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_B_4_1.jpg
Figure 5 Colon
(Glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_A_8_3.jpg
(Glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_A_8_3.jpg
Figure 6 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8743/23431_A_9_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (CACO-2, HeLa, K-562, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000069011-PITX1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000069011-PITX1
Specifications
- Immunogen
- Recombinant fragment: MPSSMGPGAV PGMPNSGLNN INNLTGSSLN SAMSPGACPY GTPASPYSVY RDTCNSSLAS LRLKSKQHSS FGYGALQGPA SGLNACQYN, corresponding to amino acids 225-314 of Human PITX1
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML621
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PITX1; paired-like homeodomain 1; BFT; CCF; POTX; PTX1; LBNBG; pituitary homeobox 1; pituitary homeo box 1; homeobox protein PITX1; pituitary otx-related factor; hindlimb expressed homeobox protein backfoot; hindlimb-expressed homeobox protein backfoot; paired-like homeodomain transcription factor 1;
- Gene ID
- 5307
- UniProt ID
- P78337
- Protein Refseq
- NP_002644
- Function
- protein binding transcription factor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-447 | Recombinant Human Anti-Human PITX1 Antibody Fab Fragment, clone U25 | IF, IP-MS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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