Recombinant Mouse anti-Human SETDB1 Monoclonal antibody (4A3)
CAT#: MOB-1037CT
Recombinant Mouse monoclonal antibody to Human SETDB1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58484/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18142/43432_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18142/43432_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18142/43432_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18142/43432_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18142/43432_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143379-SETDB1
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Specifications
- Immunogen
- This immunogen is a recombinant fragment of human SETDB1, amino acids 2-101, with the sequence: SSLPGCIGLD AATATVESEE IAELQQAVVE ELGISMEELR HFIDEELEKM DCVQQRKKQL AELETWVIQK ESEVAHVDQL FDDASRAVTN CESLVKDFY. It is fused with a tag.
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 4A3
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Concentration
- 0.5 mg/ml
- Buffer
- Preservative: None Constituents: PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- SETDB1; SET domain, bifurcated 1; ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4; histone-lysine N-methyltransferase SETDB1; H3-K9-HMTase 4; tudor domain containing 21; lysine N-methyltransferase 1E; histone H3-K9 methyltransferase 4; ERG-associated protein with SET domain; ERG-associated protein with a SET domain, ESET; histone-lysine N-methyltransferase, H3lysine-9 specific 4;
- Gene ID
- 9869
- UniProt ID
- Q15047
- Protein Refseq
- NP_001138887
- Function
- DNA binding; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity; zinc ion binding;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SETDB1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0322J | Mouse Anti-SETDB1 Recombinant Antibody (ZG-0322J) | WB, ELISA | Mouse IgG |
| ZG-0323J | Mouse Anti-SETDB1 Recombinant Antibody (ZG-0323J) | WB, IF, ELISA | Mouse IgG |
| VS3-QX1005 | Mouse Anti-SETDB1 Recombinant Antibody (clone 1E7-F3-C6) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-XY1417 | Mouse Anti-SETDB1 Recombinant Antibody (clone 5H6D4) | ELISA, WB | Mouse IgG1 |
| VS7-0425-WR849 | Mouse Anti-SETDB1 Monoclonal Antibody (VS7-0425-WR849) | WB, IF, ICC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY474 | Mouse Anti-NHP SETDB1 Recombinant Antibody (clone 5H6A12) | WB, ICC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2041 | Anti-SETDB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6515 | Anti-Human SETDB1 Immunohistochemistry Kit | IHC |
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