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    Recombinant Mouse anti-Human UBE3A Monoclonal antibody (EML2310) (CAT#: MOB-2127CT)

    Recombinant Mouse monoclonal antibody to Human UBE3A, expressed in Chinese Hamster Ovary cells(CHO).

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    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39410/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human cerebellum
    Figure 2 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong nuclear positivity in Purkinje cells and cells in molecular layer.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39410/ihc_selected.jpg
    Figure 3 Lymph node
    Figure 3 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9723/82580_A_7_8.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9723/82580_B_9_5.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9723/82580_A_8_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9723/82580_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/9723/82580_A_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000114062-UBE3A

    Specifications

    • Immunogen
    • Recombinant fragment: ETFQQLITYK VISNEFNSRN LVNDDDAIVA ASKCLKMVYY ANVVGGEVDT NHNEEDDEEP IPESSELTLQ ELLGEERRNK KGPRVDPLET ELGVKTLDCR , corresponding to amino acids 51-151 of Human UBE3A
    • Host Species
    • Mouse
    • Species Reactivity
    • Human
    • Clone
    • EML2310
    • Applications
    • Used for immunoassay techniques such as: Western Blot
    • Conjugate
    • Unconjugated

    Product Property

    • Purity
    • Protein G purified
    • Format
    • Liquid
    • Concentration
    • 0.5 mg/ml
    • Buffer
    • Preservative: None PBS, pH 7.2
    • Storage
    • Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Target

    • Alternative Names
    • UBE3A; ubiquitin protein ligase E3A; AS; ANCR; E6-AP; HPVE6A; EPVE6AP; ubiquitin-protein ligase E3A; CTCL tumor antigen se37-2; E6AP ubiquitin-protein ligase; renal carcinoma antigen NY-REN-54; human papillomavirus E6-associated protein; oncogenic protein-associated protein E6-AP; human papilloma virus E6-associated protein;
    • Function
    • acid-amino acid ligase activity; ligase activity; protein binding; transcription coactivator activity; ubiquitin-protein ligase activity;

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    See other products for "UBE3A"

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    IgG Antibodies Rabbit Monoclonal Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    MOB-2450z Mouse Anti-UBE3A Recombinant Antibody (clone 44A11) WB, ELISA, IHC Mouse IgG1
    VS3-FY1516 Recombinant Rabbit Anti-UBE3A Antibody (clone R02-1A0) WB, ICC, IF, IP Rabbit IgG

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