Recombinant Mouse Anti-IAV NA Antibody (CD6)

CAT#: PABL-227

Recombinant Mouse Antibody (CD6) is capable of binding to IAV NA, expressed in Chinese Hamster Ovary cells (CHO).

Published Data
Figure 1 Therapeutic efficacy of MAbs HF5, CD6, and 1H5 against lethal pH1N1 virus challenge in mice. DBA/2 mice (n 14 or 20 per group) were infected i.n. Figure 2 Lung samples collected on days 6, 8, and 10 p.c. from mice in the prophylactic study (5 mg/kg of MAb before CA/09 challenge) and the therapeutic study (three doses of 5 mg/kg MAb after CA/09 challenge) were homogenized, and the supernatant was tested in a plaque assay, in which MAb HF5 or CD6 was supplemented in the agar overlay. Figure 3 CA/09 mutants with the S364N mutation (left) or the N397K mutation (middle) in the NA were examined for the sensitivities of their NAs to MAbs HF5, CD6, and 3A2 in an ELLA. (Right) Results obtained with wt CA/09 NA were included for comparison. Figure 4 Prophylactic efficacy of MAbs HF5, CD6, 4E9, and 1H5 against lethal pH1N1 virus challenge in mice. DBA/2 mice (n 14 or 20 per group) were treated Figure 5 Different functional properties of MAbs HF5, CD6, 4E9, and 1H5 in vitro.

Specifications

  • Immunogen
  • Influenza a virus Neuraminidase
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native IAV NA
  • Species Reactivity
  • IAV
  • Clone
  • CD6
  • Applications
  • ELISA, FuncS

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • The antibody was validated for Function Assay. For details, refer to Published Data.

Target

  • Alternative Names
  • NA; Neuraminidase; IAV; influenza viruses
REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS
Inquiry
Navs

Customer Review

Submit a review or a question

There are currently no Customer reviews or questions for PABL-227. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Article title:
DOI/PubMed URL:
Email:
Name:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "Clone CD6"

See other products for "NA"

Select a product category from the dropdown menu below to view related products.

Specific Inquiry
Go to compare Add to compare

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Go to compare

Go to compare