Mouse Anti-IL1R2 Recombinant Antibody (NEUT-1297CQ)
CAT#: NEUT-1297CQ
This antibody is a mouse monoclonal antibody that binds specifically to IL1 Receptor 2, and it can neutralize the bioactivity of IL1 Receptor 2.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27598/60270_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27598/60270_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27598/60270_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27598/60270_A_4_6.jpg
Normal Tissue
Figure 5 Placenta
Trophoblastic cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27598/60270_A_3_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115590-IL1R2
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Specifications
- Immunogen
- Recombinant human IL1-R II EC domain
- Host Species
- Mouse
- Type
- Mouse IgG2
- Specificity
- Human IL1R2
- Species Reactivity
- Human
- Applications
- IHC, Neut, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Effective Neutralization Activity
This mouse monoclonal antibody is excellent for neutralizing the bioactivity of Human IL1R2. We confirmed its function in our neutralization assays. It specifically binds the decoy receptor and allows us to study the regulation of interleukin 1 activity in our models.
Versatile IHC And WB Tool
Besides its neutralizing capabilities, we found this antibody to be very effective in Western Blot and Immunohistochemistry. It recognizes the recombinant human IL1-R II EC domain well, providing clear bands and staining. A versatile tool for cytokine receptor research.
Q&As
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Does this antibody neutralize the biological activity of IL1R2?
A: Yes, this mouse monoclonal antibody binds specifically to IL1 Receptor 2 and is capable of neutralizing its bioactivity. It is suitable for neutralization assays (Neut) in your cytokine research.
-
What is the target of this antibody?
A: This antibody targets the Human IL1R2 (Interleukin 1 receptor type 2), which acts as a decoy receptor to inhibit the activity of IL1 ligands. The antibody recognizes the recombinant human IL1-R II EC domain.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# NEUT-1297CQ, RRID: AB_3714452)
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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|---|---|---|---|
| DrMAB-1012 | Mouse Anti-Il1r2 Recombinant Antibody (clone Praxy-1) | ELISA, FC, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
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| DrMAB-1081 | Human Anti-Il1r2 Recombinant Antibody (clone Praxy-1-1) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
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| MOB-0954CT | Recombinant Mouse anti-Human IL1R2 Monoclonal antibody (9.6) | FC, WB |
| CAT | Product Name | Application | Type |
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| NEUT-1296CQ | Mouse Anti-IL1R2 Recombinant Antibody (clone CBL086) | Neut, WB, IHC | Mouse IgG2 |
| CAT | Product Name | Application | Type |
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| NEUT-1298CQ | Mouse Anti-IL1R2 Recombinant Antibody (clone CBL451) | WB, ICC, Neut | Mouse IgG2a |
| CAT | Product Name | Application | Type |
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| NEUT-1299CQ | Mouse Anti-IL1R2 Recombinant Antibody (clone CBL456) | WB, ELISA, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
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| MOR-4006 | Rabbit Anti-IL1R2 Recombinant Antibody (clone SI68DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MOR-4254 | Rabbit Anti-IL1R2 Recombinant Antibody (clone SI334DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS3-FY236 | Recombinant Mouse Anti-IL1R2 Antibody (clone 3G1D8) | ELISA, WB, FC | Mouse IgG1 |
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