Afuco™ Anti-Human ITGA9 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-439CL)
Anti-ITGA9 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an anti-α9 integrin antibody, exerts a therapeutic effect on cancer, for example proliferation and metastasis of a cancer cell, and an inflammatory disease, for example rheumatoid arthritis, osteoarthritis, hepatitis, bronchial asthma, fibrosis, diabetes, arteriosclerosis, multiple sclerosis, granuloma, an inflammatory bowel disease (ulcerative colitis and Crohn's disease), an autoimmune disease and the like by inhibiting the α9 integrin function.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/1430_D3_3_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/1430_D3_3_selected.jpg
Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_4_1_selected.jpg
(Immunohistochemical staining of human esophagus shows membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_4_1_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_9_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_A_7_5.jpg
Figure 5 Cervix
(Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_8_3.jpg
(Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30609/69045_B_8_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HEL, SH-SY5Y, SuSa, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000144668-ITGA9
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000144668-ITGA9
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Rheumatoid Arthritis
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- ITGA9; integrin, alpha 9; RLC; ITGA4L; ALPHA-RLC; integrin alpha-9; integrin alpha-RLC
- Gene ID
- 3680
- UniProt ID
- Q13797
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Chimeric Antibody Products
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IgG Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-736LC | Human Anti-ITGA9 Recombinant Antibody (TAB-736LC) | ELISA | Chimeric (mouse/human) IgG |
| TAB-736LC-S(P) | Mouse Anti-ITGA9 Recombinant Antibody; scFv Fragment (TAB-736LC-S(P)) | ELISA | Mouse scFv |
| TAB-736LC-F(E) | Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (TAB-736LC-F(E)) | ELISA | Chimeric antibody (mouse/human) |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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