Anti-Ifi202b Intrabody [(D-Arg)9] (IAB-B022(A))
Recombinant anti-Ifi202b intrabody linked to (D-Arg)9 works within cells and directs against nucloprotein complex comprising a mammalian Ifi202 protein and foreign double stranded DNA, expressed in E. coli cells.
Specifications
- Immunogen
- mouse interferon activated gene 202B
- Host
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- mouse
- Applications
- Used for immunoassay techniques such as: Western blot; Neutralization; Functional studies
Target
- Alternative Names
- Ifi202b; interferon activated gene 202B
- Entrez Gene ID
- 26388
For lab research use only, not for diagnostic, therapeutic or any in vivo human use.
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