Recombinant Anti-mouse Ifi202b Intrabody [Tat]
CAT#: IAB-B022(T)
Recombinant anti-Ifi202b intrabody in fusion with HIV Tat works within cells and is directed against nucloprotein complex comprising a mammalian Ifi202 protein and foreign double stranded DNA, expressed in E. coli cells.
Specifications
- Immunogen
- mouse interferon activated gene 202B
- Host Species
- human
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- mouse
- Applications
- Can be useful in applications such as: Immunofluorescence; Flow Cytometry; Functional studies
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- Ifi202b; interferon activated gene 202B
- Gene ID
- 26388
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Ifi202b"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B022(A) | Recombinant Anti-mouse Ifi202b Intrabody [(D-Arg)9] | WB, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B022(G) | Recombinant Anti-mouse Ifi202b Intrabody [+36 GFP] | WB, ICC, Neut, FuncS | scFv-(+36GFP) |
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