Afuco™ Anti-Human LTB4R2 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-483CL)
Anti-LTB4R2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies specific for leukotriene B4 receptor BLT2 are used for treating asthma.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72921/1501_H5_4_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72921/1501_H5_4_selected.jpg
Figure 2 IHC staining of human fallopian tube
(Immunohistochemical staining of human fallopian tube shows distinct positivity in ciliated cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/ihc_selected.jpg
(Immunohistochemical staining of human fallopian tube shows distinct positivity in ciliated cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/ihc_selected.jpg
Figure 3 IHC staining of human vagina
(Immunohistochemical staining of human vagina shows distinct cytoplasmic positivity in superficial squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/ihc_selected.jpg
(Immunohistochemical staining of human vagina shows distinct cytoplasmic positivity in superficial squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_B_8_5.jpg
(Neuropil
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_B_8_5.jpg
Figure 5 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_8_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_8_3.jpg
Figure 6 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/49119_A_9_4.jpg
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22689/49119_A_9_4.jpg
Figure 7 Kidney
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_9_5.jpg
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_9_5.jpg
Figure 8 Testis
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_6_6.jpg
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_6_6.jpg
Figure 9 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_7_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29680/60744_A_7_8.jpg
Figure 10 RNA cell line category: Cell line enhanced (HaCaT)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213906-LTB4R2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213906-LTB4R2
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Asthma
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- LTB4R2; leukotriene B4 receptor 2; BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2; LTB4 receptor JULF2; leukotriene B4 receptor BLT2; seven transmembrane receptor BLTR2
- Gene ID
- 56413
- UniProt ID
- B4E292
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Mouse Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1271CL | Mouse Anti-LTB4R2 Recombinant Antibody (TAB-1271CL) | FC | Mouse IgG |
| TAB-1271CL-S(P) | Mouse Anti-LTB4R2 Recombinant Antibody; scFv Fragment (TAB-1271CL-S(P)) | FC | Mouse scFv |
| TAB-1271CL-F(E) | Mouse Anti-LTB4R2 Recombinant Antibody; Fab Fragment (TAB-1271CL-F(E)) | FC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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