Afuco™ Anti-Human MASP2 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-494CL)
Anti-MASP2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-MASP-2 inhibitory antibodies can be used for treatment of immune and inflammatory disorders.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/if_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/if_selected.jpg
Figure 2 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows distinct plasma positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/ihc_selected.jpg
(Immunohistochemical staining of human duodenum shows distinct plasma positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/ihc_selected.jpg
Figure 3 IHC staining of human skin
(Immunohistochemical staining of human skin shows extracellular positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29314/ihc_selected.jpg
(Immunohistochemical staining of human skin shows extracellular positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29314/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_B_7_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_B_7_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_9_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_9_3.jpg
Figure 6 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_7_4.jpg
Figure 7 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_8_5.jpg
Figure 8 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29313/72652_A_6_6.jpg
Figure 9 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000009724-MASP2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000009724-MASP2
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases; Autoimmune Diseases
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- MASP2; mannan-binding lectin serine peptidase 2; sMAP; MAP19; MASP-2; MASP1P1; mannan-binding lectin serine protease 2; small MBL-associated protein; MBL-associated serine protease 2; MBL-associated plasma protein of 19 kD; mannan-binding lectin serine protease 1 pseudogene 1; mannose-binding protein-associated serine protease 2; mannan-binding lectin serine peptidase 1 pseudogene 1
- Gene ID
- 10747
- UniProt ID
- O00187
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Mouse Antibodies
Chimeric Antibodies
Human Antibodies
ScFv-Fc Chimeras
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1914z | Mouse Anti-MASP2 Recombinant Antibody (clone 30D10) | WB, ELISA, IF, IP | Mouse IgG1, κ |
| MRO-0966-CN | Recombinant Mouse Anti-MASP2 Monoclonal Antibody (F3-4) | WB | Mouse IgG2b |
| MOB-0791-YJ | Rat Anti-MASP2 Recombinant Antibody (CBM85D) | IA, WB | Rat IgG1 |
| MOB-0807-YJ | Rat Anti-MASP2 Recombinant Antibody (CBM101D) | IA, WB | Rat IgG1 |
| VS-0723-WK7 | Human Anti-MASP2 Recombinant Antibody (clone Narsoplimab) | FC | Human IgG4 |
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