Afuco™ Anti-Human MCM6 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-497CL)
Anti-MCM6 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The novel monoclonal antibodies that specifically bind to MCM6 are used for diagnosing high-grade cervical disease comprising detecting overexpression of MCM6.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 Tonsil
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_6_8_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_6_8_val_selected.jpg
Figure 2 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_9_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_9_8.jpg
Figure 3 Colon
(Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes - Gradient Gradient: Descending Enterocytes - Goblet cells Staining: Medium Intensity: Strong Quantity: <25% Mucosal lymphoid cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_9_3.jpg
(Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Medium Intensity: Strong Quantity: <25% Enterocytes - Gradient Gradient: Descending Enterocytes - Goblet cells Staining: Medium Intensity: Strong Quantity: <25% Mucosal lymphoid cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_9_3.jpg
Figure 4 Kidney
(Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_9_5.jpg
(Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_9_5.jpg
Figure 5 Testis
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_6_6.jpg
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4818/14021_A_6_6.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076003-MCM6
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076003-MCM6
Specifications
- Host Species
- Mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cervical Disease
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- MCM6; minichromosome maintenance complex component 6; Mis5; P105MCM; MCG40308; DNA replication licensing factor MCM6; minichromosome maintenance deficient (mis5, S. pombe) 6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)
- Gene ID
- 4175
- UniProt ID
- Q14566
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
IgG Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0742CL | Mouse Anti-MCM6 Recombinant Antibody (TAB-0742CL) | ELISA, ICC, WB, IHC | Mouse IgG2a |
| TAB-0742CL-S(P) | Mouse Anti-MCM6 Recombinant Antibody; scFv Fragment (TAB-0742CL-S(P)) | ELISA | Mouse scFv |
| TAB-0742CL-F(E) | Mouse Anti-MCM6 Recombinant Antibody; Fab Fragment (TAB-0742CL-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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