Afuco™ Anti-Human MMP8 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-512CL)
Anti-MMP8 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies against MMP8 can be used to treat inflammation, such as but not limited to systemic inflammatory response syndrome, sepsis, LPS induced inflammation, and other inflammatory diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21763/1984_B2_8_cr5e5901ef3d8ad_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21763/1984_B2_8_cr5e5901ef3d8ad_selected.jpg
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21221/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells of red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21221/ihc_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22935/50813_B_6_4.jpg
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22935/50813_B_6_4.jpg
Figure 4 RNA cell line category: Cell line enriched (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118113-MMP8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118113-MMP8
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- 95% by HPLC
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- MMP8; matrix metallopeptidase 8 (neutrophil collagenase); HNC; CLG1; MMP-8; PMNL-CL; neutrophil collagenase; collagenase 2; PMNL collagenase; PMN leukocyte collagenase; matrix metalloproteinase-8; matrix metalloproteinase 8 (neutrophil collagenase)
- Gene ID
- 4317
- UniProt ID
- P22894
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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