Anti-Human MTM1 Antibody, Research Grade Biosimilar
CAT#: TAB-683CL
Recombinant Humanized expressed in CHO binding to Human MTM1. This chimeric polypeptides comprising myotubularin 1 (MTMI) polypeptides and an internalising moiety which can be a monoclonal antibody 3E10. It can be used as a further therapeutic agent of treating Myotubular Myopathy.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules and cells in glomeruli.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/26608_A_7_5_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10665/26604_A_6_2_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & Cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/57_F11_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 5 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & Cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/56_F11_1_blue_red_green.jpg
Normal Tissue
Figure 6 Colon
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/26608_A_7_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/26608_A_9_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/26608_A_6_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10008/26608_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171100-MTM1
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Specifications
- Derivation
- Chimeric
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Myotubular Myopathy
Product Property
- Purity
- >95% by HPLC
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- MTM1; myotubularin 1; CNM; MTMX; XLMTM; myotubularin; phosphatidylinositol-3-phosphate phosphatase; phosphatidylinositol-3,5-bisphosphate 3-phosphatase
- Gene ID
- 4534
- UniProt ID
- A0A024RC06
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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See other products for "MTM1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1762-VHH | Recombinant Anti-Human MTM1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3168z | Mouse Anti-MTM1 Recombinant Antibody (clone 36B2) | WB, IP, IF, IHC, ELISA | Mouse IgG2b, κ |
| MOB-0938MZ | Recombinant Mouse Anti-Human MTM1 Antibody | IHC-P | Mouse antibody |
| HPAB-1014WJ | Human Anti-MTM1 Recombinant Antibody (HPAB-1014WJ) | IHC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1014WJ-S(P) | Mouse Anti-MTM1 Recombinant Antibody; scFv Fragment (HPAB-1014WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1014WJ-F(E) | Mouse Anti-MTM1 Recombinant Antibody; Fab Fragment (HPAB-1014WJ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4567 | Anti-MTM1 Immunohistochemistry Kit | IHC |
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