Anti-Human MUC13 Recombinant Antibody (TCC56)
CAT#: TAB-440MZ
This clone mAb TCC56 was secreted from hybridoma and then was produced as a recombinant antibody, which was an IgG3κ isotype. Biotinylated proteins were at 35 KDa by immunoprecipitation using mAb TCC56 under reducing conditions. MUC13 was identified as a possible candidate for the 35 KDa molecule by mass spectrometry. Flow cytometry results indicated that mAb TCC56 reacted with transfectants expressing MUC13.
Published Data
Gene Expression
IP
Figure 1 Lysates of TCC-PAN2 cells were immunoprecipitated with mAb TCC56.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
FC
Figure 2 Flow cytometry results indicate the reactivity of mAb TCC56 or P3 (a negative control mouse IgG1) with CHO-K1 cells transfected with a MUC13 expression vector. The mAb TCC56 reacted with transfectants expressing MUC13.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
FC
Figure 3 Flow cytometry results shows the reactivity of mAb TCC56 with TCC-PAN 2 cells.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
Cyt
Figure 4 mAb TCC56-DT3C conjugate induced TCC-PAN2 cell death.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
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Normal Tissue
Figure 1 High expression in duodenum
Endocrine cells Staining: Low Intensity: Weak Enterocytes - Microvilli Staining: Low Intensity: Weak Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45163/100517_A_9_2.jpg
Normal Tissue
Figure 2 Colon
Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/45163/100517_A_8_3.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173702-MUC13
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Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- TCC56
- Applications
- Cyt, FC, IP
- Related Disease
- Pancreatic cancer
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity, Flow Cytotoxicityometry, Immunoprecipitation.
Target
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(Creative Biolabs Cat# TAB-440MZ, RRID: AB_3111946)
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-440MZ-S(P) | Anti-Human MUC13 Recombinant Antibody scFv Fragment (TCC56) | IP | |
| TAB-440MZ-F(E) | Anti-Human MUC13 Recombinant Antibody Fab Fragment (TCC56) | IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1623LY-S(P) | Human Anti-MUC13 Recombinant Antibody (clone C4); scfv Fragment | IHC, WB, IP, ELISA, FC | Humanized scfv |
| HPAB-1624LY-S(P) | Human Anti-MUC13 Recombinant Antibody (clone C7); scfv Fragment | IHC, WB, IP, ELISA, FC | Humanized scfv |
| HPAB-1625LY-S(P) | Human Anti-MUC13 Recombinant Antibody (clone C14); scfv Fragment | IHC, WB, IP, ELISA, FC | Humanized scfv |
| HPAB-1626LY-S(P) | Human Anti-MUC13 Recombinant Antibody (clone C18); scfv Fragment | IHC, WB, IP, ELISA, FC | Humanized scfv |
| HPAB-0001-SJF-S(P) | Mouse Anti-MUC13 Recombinant Antibody scFv Fragment (HPAB-0001-SJF-S(P)) | WB, IHC, ELISA, IP, FC, IF, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1623LY | Human Anti-MUC13 Recombinant Antibody (clone C4) | IHC, WB, IP, ELISA, FC | Humanized IgG |
| HPAB-1624LY | Human Anti-MUC13 Recombinant Antibody (clone C7) | IHC, WB, IP, ELISA, FC | Humanized IgG |
| VS3-FY975 | Recombinant Mouse Anti-MUC13 Antibody (clone 8B2A7) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-FY976 | Recombinant Mouse Anti-MUC13 Antibody (clone 8B2C4) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS13-YC748 | Rabbit Anti-MUC13 Recombinant Antibody (VS13-YC748) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1623LY-F(E) | Human Anti-MUC13 Recombinant Antibody (clone C4); Fab Fragment | IHC, WB, IP, ELISA, FC | Humanized Fab |
| HPAB-1624LY-F(E) | Human Anti-MUC13 Recombinant Antibody (clone C7); Fab Fragment | IHC, WB, IP, ELISA, FC | Humanized Fab |
| HPAB-1625LY-F(E) | Human Anti-MUC13 Recombinant Antibody (clone C14); Fab Fragment | IHC, WB, IP, ELISA, FC | Humanized Fab |
| HPAB-1626LY-F(E) | Human Anti-MUC13 Recombinant Antibody (clone C18); Fab Fragment | IHC, WB, IP, ELISA, FC | Humanized Fab |
| HPAB-0001-SJF-F(E) | Mouse Anti-MUC13 Recombinant Antibody Fab Fragment (HPAB-0001-SJF-F(E)) | WB, IHC, ELISA, IP, FC, IF, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC151 | Recombinant Anti-MUC13 Vesicular Antibody, EV Displayed (VS-0425-YC151) | Cyt, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4577 | Anti-MUC13 Immunohistochemistry Kit | IHC |
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