Anti-Human MUC13 Recombinant Antibody (TCC56) (CAT#: TAB-440MZ)
This clone mAb TCC56 was secreted from hybridoma and then was produced as a recombinant antibody, which was an IgG3κ isotype. Biotinylated proteins were at 35 KDa by immunoprecipitation using mAb TCC56 under reducing conditions. MUC13 was identified as a possible candidate for the 35 KDa molecule by mass spectrometry. Flow cytometry results indicated that mAb TCC56 reacted with transfectants expressing MUC13.
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IP
Figure 1 Lysates of TCC-PAN2 cells were immunoprecipitated with mAb TCC56.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
FC
Figure 2 Flow cytometry results indicate the reactivity of mAb TCC56 or P3 (a negative control mouse IgG1) with CHO-K1 cells transfected with a MUC13 expression vector. The mAb TCC56 reacted with transfectants expressing MUC13.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
FC
Figure 3 Flow cytometry results shows the reactivity of mAb TCC56 with TCC-PAN 2 cells.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
Cyt
Figure 4 mAb TCC56-DT3C conjugate induced TCC-PAN2 cell death.
Nishii, Y., Yamaguchi, M., Kimura, Y., Hasegawa, T., Aburatani, H., Uchida, H., ... & Sakuma, Y. (2015). A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. International journal of oncology, 46(4), 1781-1787.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- TCC56
- Applications
- Cyt, FC, IP
- Related Disease
- Pancreatic cancer
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity, Flow Cytotoxicityometry, Immunoprecipitation.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-440MZ-S(P) | Anti-Human MUC13 Recombinant Antibody scFv Fragment (TCC56) | IP | |
| TAB-440MZ-F(E) | Anti-Human MUC13 Recombinant Antibody Fab Fragment (TCC56) | IP |
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(Creative Biolabs Cat# TAB-440MZ, RRID: AB_3111946)
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