Afuco™ Anti-Human PLA2G2A ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-682CL)
Anti-PLA2G2A ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. It is an isolated antibody against human sPLA2-IIA which play a key role in various biological processes including homeostasis of cellular membranes, lipid digestion, host defense, signal transduction, and production of lipid mediators. Therefore, it can be used in inflammation and atherosclerosis.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human duodenum
(Immunohistochemical staining of human testis shows high expression in duodenum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_8_2_selected.jpg
(Immunohistochemical staining of human testis shows high expression in duodenum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_8_2_selected.jpg
Figure 2 Cerebral cortex
(Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_B_7_5.jpg
(Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_B_7_5.jpg
Figure 3 Small intestine
(Paneth cells
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_5_2.jpg
(Paneth cells
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_5_2.jpg
Figure 4 Colon
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_8_3.jpg
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_8_3.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_8_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_8_5.jpg
Figure 6 Testis
(Preleptotene spermatocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Round or early spermatids
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_4_6.jpg
(Preleptotene spermatocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Round or early spermatids
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15236/41162_A_4_6.jpg
Figure 7 RNA cell line category: Group enriched (Hep G2, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188257-PLA2G2A/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188257-PLA2G2A/subcellular
Specifications
- Host Species
- Rabbit
- Derivation
- Rabbit
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammation; Atherosclerosis
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- PLA2G2A; phospholipase A2, group IIA (platelets, synovial fluid); MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2; phospholipase A2, membrane associated; NPS-PLA2; GIIC sPLA2; group IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; non-pancreatic secretory phospholipase A2
- Gene ID
- 5320
- UniProt ID
- A0A024RA96
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1823z | Mouse Anti-PLA2G2A Recombinant Antibody (clone 30C11) | WB, IP | Mouse IgG2b |
| HPAB-0422-YC | Human Anti-PLA2G2A Recombinant Antibody (HPAB-0422-YC) | ELISA | Human IgG |
| HPAB-0423-YC | Human Anti-PLA2G2A Recombinant Antibody (HPAB-0423-YC) | ELISA | Human IgG |
| HPAB-0424-YC | Human Anti-PLA2G2A Recombinant Antibody (HPAB-0424-YC) | ELISA | Human IgG |
| VS3-FY1146 | Recombinant Rabbit Anti-PLA2G2A Antibody (clone R09-4F9) | WB | Rabbit IgG |
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