Mouse Anti-RAMP1 Recombinant Antibody (clone JB3) (CAT#: NS-069CN)
The anti-RAMP1 antibody is capable of binding to RAMP1, RAMP2 or RAMP3. The antibody can be used in the treatment of tumors.
Specific Inquiry
FuncS
Figure 1 The effect of the monoclonal antibodies on the growth of SW-13 cells in vitro.
Monoclonal anti-RAMP-3 antibodies were tested for their ability to induce inhibition of proliferation of SW-13 (adrenocarcinoma cells). The concentration of 1 :50 equates to about 5ng per well final concentration.
FuncS
Figure 2 A MTT assay assessing the rate of proliferation in the U-87 glioblastoma cell line in the presence of antibody JB3 at varying concentrations (after 8 days of culture).
FuncS
Figure 3 A MTT assay assessing the rate of proliferation in the MDA-MB-436-GFP breast cancer cell line in the presence of antibody JB3 at varying concentrations (after 8 days of culture).
FuncS
Figure 4 A MTT assay assessing the rate of proliferation in the PC-3 prostate cancer cell line in the presence of antibody JB3 at a concentration of 10Mg (after 8 days of culture).
Apop
Figure 5 An apoptosis assay assessing the levels of caspase-3 a marker in U-87 glioblastoma cancer cell line in the presence of antibody JB3 and JF2.
Apop
Figure 6 An apoptosis assay assessing the levels of caspase-3 a marker in a MDA-MB-436-GFP breast cancer cell line in the presence of antibody JB3 and JF2.
Specifications
- Immunogen
- A peptide corresponding to an extracellular domain of RAMP-3
- Host Species
- Mouse
- Type
- Mouse IgM
- Specificity
- Human RAMP1
- Species Reactivity
- Human
- Clone
- JB3
- Applications
- ELISA, WB, Apop, FuncS
- Related Disease
- Tumor
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Apoptosis, Functional Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Neuroscience Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2606z | Mouse Anti-RAMP1 Recombinant Antibody (clone 32A11) | WB, ELISA, IP | Mouse IgG2b, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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