Recombinant Mouse Anti-SIGLEC5 Antibody (1A5) (CAT#: NEUT-1961CQ)
This antibody is a mouse monoclonal antibody that binds specifically to SIGLEC5, and it can neutralize the bioactivity of SIGLEC5.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9085/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in subsets of bone marrow poietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9085/ihc_selected.jpg
Figure 2 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24900/58939_A_8_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24900/58939_A_8_4.jpg
Figure 3 Bone marrow
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24900/58939_B_4_4.jpg
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24900/58939_B_4_4.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24900/58939_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24900/58939_A_8_8.jpg
Figure 5 RNA cell line category: Group enriched (HMC-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105501-SIGLEC5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105501-SIGLEC5
Specifications
- Immunogen
- Siglec-5-Fc protein, containing entire extracellular region of siglec-5 fused with the Fc region of human IgG1.
- Host Species
- Mouse
- Type
- IgG1
- Specificity
- This antibody cross reacts with SEGLEC14.
- Species Reactivity
- Human
- Clone
- 1A5
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry-Frozen; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunocytochemistry/Immunofluorescence; Immunoprecipitation; Neutralization; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purification
- IgG fraction
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze-thaw cycles.
Target
- Alternative Names
- SIGLEC5; sialic acid binding Ig like lectin 5; CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5
- Gene ID
- 8778
- UniProt ID
- O15389
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Neutralizing Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2886z | Mouse Anti-SIGLEC5 Recombinant Antibody (clone 14F8) | ELISA, FC, ICC, IHC, IP | Mouse IgG1 |
| MOB-1377CT | Recombinant Mouse anti-Human SIGLEC5 Monoclonal antibody (2B6) | ELISA, FC, ICC/IF, IHC-Fr, IP, Neut, WB |
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