Afuco™ Anti-Human SLC29A1 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-550CL
Anti-SLC29A1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies that recognize hENTl are useful as companion diagnostics for established cancer drugs such as nucleoside analogue drugs and/or drugs derived from nucleoside analogues. For example, the hENTl antibodies are useful in conjunction with chemotherapy agents such as pyrimidine derivatives including, for example, cytarabine, gemcitabine, azacytidine, and derivatives thereof, and purine derivatives including, for example, fludarabine, cladribine, clofarabine and derivatives thereof.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12384/53738_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112759-SLC29A1
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Specifications
- Host Species
- Mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- SLC29A1; solute carrier family 29 (equilibrative nucleoside transporter), member 1; ENT1; equilibrative nucleoside transporter 1; nucleoside transporter, es-type; solute carrier family 29 member 1; solute carrier family 29, member 1; equilibrative NBMPR-sensitive nucleoside transporter; solute carrier family 29 (nucleoside transporters), member 1; equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter
- Gene ID
- 2030
- UniProt ID
- Q99808
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2662z | Mouse Anti-SLC29A1 Recombinant Antibody (clone 37B3) | WB, ELISA, IF, IHC, IP | Mouse IgG2a, κ |
| MOB-164CQ | Mouse Anti-Human SLC29A1 Antibody | ELISA, WB, IP, IF, IHC-P | Mouse IgG2a, κ |
| HPAB-0540-YJ | Mouse Anti-SLC29A1 Recombinant Antibody (HPAB-0540-YJ) | ELISA, WB | Mouse IgG1 |
| HPAB-0541-YJ | Human Anti-SLC29A1 Recombinant Antibody (HPAB-0541-YJ) | ELISA, WB | Chimeric (mouse/human) IgG1 |
| VS13-YC1067 | Rabbit Anti-SLC29A1 Recombinant Antibody (VS13-YC1067) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0540-YJ-S(P) | Mouse Anti-SLC29A1 Recombinant Antibody; scFv Fragment (HPAB-0540-YJ-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0541-YJ-S(P) | Mouse Anti-SLC29A1 Recombinant Antibody; scFv Fragment (HPAB-0541-YJ-S(P)) | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0540-YJ-F(E) | Mouse Anti-SLC29A1 Recombinant Antibody; Fab Fragment (HPAB-0540-YJ-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0541-YJ-F(E) | Human Anti-SLC29A1 Recombinant Antibody; Fab Fragment (HPAB-0541-YJ-F(E)) | ELISA, WB | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC554 | Recombinant Anti-SLC29A1 Vesicular Antibody, EV Displayed (VS-0425-YC554) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6659 | Anti-SLC29A1 Immunohistochemistry Kit | IHC |
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