Recombinant Mouse Anti-T. cruzi trans-sialidase Antibody (13G9) (CAT#: PABL-711)
Recombinant Mouse Antibody (13G9) is capable of binding to T. cruzi trans-sialidase , expressed in Chinese Hamster Ovary cells (CHO). This antibody could effectively block its sialylation and host cell invasion capacities.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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FC
Figure 1 Flow cytometry analysis of TSs parasite expression.
TS expression on T-O, T-iTS, and T-aTS parasites was followed with mAb 13G9. Isotype control, T-O parasites, were treated with secondary antibodies only.
Pascuale, C. A., Burgos, J. M., Postan, M., Lantos, A. B., Bertelli, A., Campetella, O., & Leguizamón, M. S. (2017). Inactive trans-sialidase expression in iTS-null Trypanosoma cruzi generates virulent trypomastigotes. Frontiers in cellular and infection microbiology, 7, 430.
IF
Figure 2 Surface expression pattern of TSs.
Confocal images show a similar surface expression pattern of TSs (observed by mAb 13G9 in red).
Pascuale, C. A., Burgos, J. M., Postan, M., Lantos, A. B., Bertelli, A., Campetella, O., & Leguizamón, M. S. (2017). Inactive trans-sialidase expression in iTS-null Trypanosoma cruzi generates virulent trypomastigotes. Frontiers in cellular and infection microbiology, 7, 430.
Specifications
- Immunogen
- T. cruzi trans-sialidase
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native T. cruzi trans-sialidase
- Species Reactivity
- T. cruzi
- Clone
- 13G9
- Applications
- FC, IF
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry and Immunofluorescence.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Single Domain Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-048 | Recombinant Anti-T. cruzi trans-sialidase VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
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