Afuco™ Anti-Human TMPRSS11E ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-597CL
Anti-TMPRSS11E ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibody against TMPRSS11E and TMPRSS11E is highly expressed on the cell membranes of cancer cell lines in flow cytometry. This antibody exhibits antibody-dependent cell-mediated cytotoxicity activity (ADCC activity) and antitumor effect based on internalization activity and is promising as a therapeutic target. Moreover, this antibody has neutralization activity against protease activity and is also expected to have effect brought about by the inhibition of TMPRSS11E functions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43816/1941_D3_2_selected.jpg
Normal Tissue
Figure 2 High expression in esophagus
Squamous epithelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_B_4_1.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HaCaT, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087128-TMPRSS11E
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Specifications
- Host Species
- Chimeric (human/mouse)
- Derivation
- Chimeric (human/mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-713CT | Mouse Anti-TMPRSS11E Recombinant Antibody (TAB-713CT) | ELISA, FC, IHC, Neut | Mouse IgG2a, κ |
| TAB-713CT-S(P) | Mouse Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (TAB-713CT-S(P)) | ELISA, FC, IHC, Neut | Mouse scFv |
| TAB-713CT-F(E) | Mouse Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (TAB-713CT-F(E)) | ELISA, FC, IHC, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP826-YC | Mouse Anti-TMPRSS11E Recombinant Antibody (HPAB-AP826-YC) | FC, FuncS | Mouse IgG1, κ |
| HPAB-AP827-YC | Human Anti-TMPRSS11E Recombinant Antibody (HPAB-AP827-YC) | FC, FuncS | Chimeric (mouse/human) IgG1, κ |
| HPAB-AP828-YC | Human Anti-TMPRSS11E Recombinant Antibody (HPAB-AP828-YC) | FC, FuncS | Chimeric (mouse/human) IgG1, κ |
| HPAB-AP829-YC | Mouse Anti-TMPRSS11E Recombinant Antibody (HPAB-AP829-YC) | ELISA, IB, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP826-YC-S(P) | Mouse Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP826-YC-S(P)) | FC, ADCC, FuncS | Mouse scFv |
| HPAB-AP827-YC-S(P) | Human Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP827-YC-S(P)) | FC, ADCC, FuncS | Mouse scFv |
| HPAB-AP828-YC-S(P) | Human Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP828-YC-S(P)) | FC, ADCC, Neut, FuncS | Mouse scFv |
| HPAB-AP829-YC-S(P) | Mouse Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP829-YC-S(P)) | ELISA, IB, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP826-YC-F(E) | Mouse Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP826-YC-F(E)) | FC, ADCC, FuncS | Mouse Fab |
| HPAB-AP827-YC-F(E) | Human Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP827-YC-F(E)) | FC, ADCC, FuncS | Chimeric (mouse/human) Fab |
| HPAB-AP828-YC-F(E) | Human Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP828-YC-F(E)) | FC, ADCC, Neut, FuncS | Chimeric (mouse/human) Fab |
| HPAB-AP829-YC-F(E) | Mouse Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP829-YC-F(E)) | ELISA, IB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC92 | Recombinant Anti-TMPRSS11E Vesicular Antibody, EV Displayed (VS-0425-YC92) | ELISA, FC, Neut, Cell-uptake |
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