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TMPRSS11E
The monoclonal antibody against TMPRSS11E and TMPRSS11E is highly expressed on the cell membranes of cancer cell lines in flow cytometry. This antibody exhibits antibody-dependent cell-mediated cytotoxicity activity (ADCC activity) and antitumor effect based on internalization activity and is promising as a therapeutic target. Moreover, this antibody has neutralization activity against protease activity and is also expected to have effect brought about by the inhibition of TMPRSS11E functions.
Protein class
Enzymes
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (Ionocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HaCaT, OE19)
Interaction
Forms a heterodimer with SERPINA5 and SERPINE1.
Molecular function
Hydrolase, Protease, Serine protease
More Types Infomation
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- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, Neut
- Mouse Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP829-YC-F(E)) (HPAB-AP829-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IB, IHC
- Anti-Human TMPRSS11E Recombinant Antibody (TAB-619CL)
-
- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: Antibody
- Human Anti-TMPRSS11E Antibody, mRNA (TAB-619CL-mRNA)
-
- Species Reactivity: Human
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, Neut
- Mouse Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP829-YC-S(P)) (HPAB-AP829-YC-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IB, IHC
- Human Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP828-YC-S(P)) (HPAB-AP828-YC-S(P))
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ADCC, Neut, FuncS
- Human Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP827-YC-S(P)) (HPAB-AP827-YC-S(P))
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ADCC, FuncS
- Mouse Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (HPAB-AP826-YC-S(P)) (HPAB-AP826-YC-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ADCC, FuncS
- Mouse Anti-TMPRSS11E Recombinant Antibody (HPAB-AP829-YC) (HPAB-AP829-YC)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IB, IHC
- Human Anti-TMPRSS11E Recombinant Antibody (HPAB-AP828-YC) (HPAB-AP828-YC)
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: FC, FuncS
- Human Anti-TMPRSS11E Recombinant Antibody (HPAB-AP827-YC) (HPAB-AP827-YC)
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: FC, FuncS
- Mouse Anti-TMPRSS11E Recombinant Antibody (HPAB-AP826-YC) (HPAB-AP826-YC)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, FuncS
- Human Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP828-YC-F(E)) (HPAB-AP828-YC-F(E))
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FC, ADCC, Neut, FuncS
- Human Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP827-YC-F(E)) (HPAB-AP827-YC-F(E))
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FC, ADCC, FuncS
- Mouse Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (HPAB-AP826-YC-F(E)) (HPAB-AP826-YC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ADCC, FuncS
-
- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: ELISA, FC, IHC, Neut
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For Research Use Only. Not For Clinical Use.