Anti-Human TMPRSS11E Recombinant Antibody (CAT#: TAB-619CL)
Recombinant Chimeric (human/mouse) monoclonal antibody expressed in CHO binding to Human TMPRSS11E. The monoclonal antibody against TMPRSS11E and TMPRSS11E is highly expressed on the cell membranes of cancer cell lines in flow cytometry. This antibody exhibits antibody-dependent cell-mediated cytotoxicity activity (ADCC activity) and antitumor effect based on internalization activity and is promising as a therapeutic target. Moreover, this antibody has neutralization activity against protease activity and is also expected to have effect brought about by the inhibition of TMPRSS11E functions.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43816/1941_D3_2_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43816/1941_D3_2_selected.jpg
Figure 2 High expression in esophagus
(Squamous epithelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_B_4_1.jpg
(Squamous epithelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_B_4_1.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_A_8_5.jpg
Figure 4 Testis
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51062/128330_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (HaCaT, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087128-TMPRSS11E
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087128-TMPRSS11E
Specifications
- Host Species
- mouse
- Derivation
- Chimeric (human/mouse)
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- TMPRSS11E; transmembrane protease, serine 11E; DESC1; TMPRSS11E2; transmembrane protease serine 11E; serine protease DESC1; transmembrane protease serine 11E2; transmembrane protease, serine 11E2
- Gene ID
- 28983
- UniProt ID
- Q9UL52
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-713CT | Mouse Anti-TMPRSS11E Recombinant Antibody (TAB-713CT) | ELISA, FC, IHC, Neut | Mouse IgG2a, κ |
| TAB-713CT-S(P) | Mouse Anti-TMPRSS11E Recombinant Antibody; scFv Fragment (TAB-713CT-S(P)) | ELISA, FC, IHC, Neut | Mouse scFv |
| TAB-713CT-F(E) | Mouse Anti-TMPRSS11E Recombinant Antibody; Fab Fragment (TAB-713CT-F(E)) | ELISA, FC, IHC, Neut | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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