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    Rabbit Anti-TP53BP1 Recombinant Antibody (clone DS3645AB) (CAT#: MOR-3645)

    Recombinant Rabbit anti-TP53BP1 monoclonal antibody for WB, IHC-P, ICC/IF, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8788/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22133/if_selected.jpg
    Figure 3 IHC staining of human cerebellum
    Figure 3 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong nuclear positivity.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22133/ihc_selected.jpg
    Figure 4 IHC staining of human prostate
    Figure 4 IHC staining of human prostate
    (Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/ihc_selected.jpg
    Figure 5 IHC staining of human testis
    Figure 5 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferous ducts and Leydig cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79980/170627_A_5_6_selected.jpg
    Figure 6 IF staining of human cell line U-251 MG
    Figure 6 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22133/189_A4_1_blue_red_green.jpg
    Normal Tissue
    Figure 7 Cerebral cortex
    Figure 7 Cerebral cortex
    (Glial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_B_8_5.jpg
    Figure 8 Nasopharynx
    Figure 8 Nasopharynx
    (Respiratory epithelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_B_7_2.jpg
    Figure 9 Colon
    Figure 9 Colon
    (Endocrine cells
    Staining: High
    Intensity: Strong
    Enterocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Goblet cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Mucosal lymphoid cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_8_3.jpg
    Figure 10 Liver
    Figure 10 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_7_4.jpg
    Figure 11 Kidney
    Figure 11 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_8_5.jpg
    Figure 12 Testis
    Figure 12 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Peritubular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Preleptotene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_4_6.jpg
    Figure 13 Lymph node
    Figure 13 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_8_8.jpg
    RNA Expression
    Figure 14 RNA cell line category: Low cell line specificity
    Figure 14 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    *
    Figure 14 RNA cell line category: Low cell line specificity
    Figure 14 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000067369-TP53BP1

    Specifications

    • Immunogen
    • Synthetic peptide within Human 53BP1, aa 900-1000 (Cysteine residue).
    • Host Species
    • Rabbit
    • Derivation
    • Phage display library
    • Type
    • Rabbit IgG
    • Specificity
    • Human TP53BP1
    • Species Reactivity
    • Human
    • Clone
    • DS3645AB
    • Applications
    • WB, IHC-P, ICC, IF
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Protein A purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • TP53; p202; 53BP1; TDRD30; p53BP1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TP53BP1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibodies FC Reagents & Kits IHC Kits & Antibodies
    CAT Product Name Application Type
    DrMAB-617 Human Anti-TP53BP1 Recombinant Antibody (clone D535) ELISA, IP-MS Human IgG
    MRO-0009-CN Rabbit Anti-TP53BP1 Recombinant Antibody (clone JA66-11) WB, IF, IHC, FC Rabbit IgG
    ZG-428C Human Anti-TP53BP1 Recombinant Antibody (ZG-428C) ELISA, IP Human IgG1, κ
    VS3-QX1152 Mouse Anti-TP53BP1 Recombinant Antibody (clone 4G1C6) WB, IHC, ICC, FC, ELISA Mouse IgG1
    VS7-0425-WR1037 Mouse Anti-TP53BP1 Recombinant Antibody (clone 6B3E10) IHC, FC Mouse IgG1

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