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    CytoStream™ Rabbit Anti-TP53BP1 Recombinant Antibody (VS13-YC1177) (CAT#: VS13-YC1177)

    The CytoStream™ Rabbit Anti-TP53BP1 Recombinant Antibody is specific for human, mouse and rat TP53BP1. TP53BP1 encodes a DNA repair pathway protein promoting non-homologous end joining, influencing recombination and telomere protection, with spliced variants. The anti-TP53BP1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8788/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22133/if_selected.jpg
    Figure 3 IHC staining of human cerebellum
    Figure 3 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong nuclear positivity.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22133/ihc_selected.jpg
    Figure 4 IHC staining of human prostate
    Figure 4 IHC staining of human prostate
    (Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/ihc_selected.jpg
    Figure 5 IHC staining of human testis
    Figure 5 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferous ducts and Leydig cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79980/170627_A_5_6_selected.jpg
    Figure 6 IF staining of human cell line U-251 MG
    Figure 6 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22133/189_A4_1_blue_red_green.jpg
    Normal Tissue
    Figure 7 Cerebral cortex
    Figure 7 Cerebral cortex
    (Glial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_B_8_5.jpg
    Figure 8 Nasopharynx
    Figure 8 Nasopharynx
    (Respiratory epithelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_B_7_2.jpg
    Figure 9 Colon
    Figure 9 Colon
    (Endocrine cells
    Staining: High
    Intensity: Strong
    Enterocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Goblet cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Mucosal lymphoid cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_8_3.jpg
    Figure 10 Liver
    Figure 10 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_7_4.jpg
    Figure 11 Kidney
    Figure 11 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_8_5.jpg
    Figure 12 Testis
    Figure 12 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Peritubular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Preleptotene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_4_6.jpg
    Figure 13 Lymph node
    Figure 13 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4083/11369_A_8_8.jpg
    RNA Expression
    Figure 14 RNA cell line category: Low cell line specificity
    Figure 14 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    *
    Figure 14 RNA cell line category: Low cell line specificity
    Figure 14 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000067369-TP53BP1

    Specifications

    • Immunogen
    • Recombinant human 53BP1, aa 1-50.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse and Rat TP53BP1
    • Species Reactivity
    • Human, Mouse, Rat
    • Applications
    • WB, ICC, IF, IHC-P, FC
    • Conjugate
    • NONE

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/500-1/1000
      Immunocytochemistry (ICC): 1/100-1/500
      Immunofluorescence (IF): 1/100-1/500
      Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
      Flow cytometry (FC): 1/50-1/100

    Target

    • Alternative Names
    • Tumor Protein P53 Binding Protein 1; P53-Binding Protein 1; P53BP1; 53BP1; Tumor Suppressor P53-Binding Protein 1; Tumor Protein P53-Binding Protein, 1;
    • Long Name
    • Tumor Protein P53 Binding Protein 1
    • Cellular Localization
    • Nucleus; Chromosome

    Recommended Products

    Secondary Antibody

    Isotype Control

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TP53BP1"

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    Please select product type
    IgG Antibody Products Rabbit Monoclonal Antibody Products
    CAT Product Name Application Type
    DrMAB-617 Human Anti-TP53BP1 Recombinant Antibody (clone D535) ELISA, IP-MS Human IgG
    MRO-0009-CN Rabbit Anti-TP53BP1 Recombinant Antibody (clone JA66-11) WB, IF, IHC, FC Rabbit IgG
    ZG-428C Human Anti-TP53BP1 Recombinant Antibody (ZG-428C) ELISA, IP Human IgG1, κ
    VS3-QX1152 Mouse Anti-TP53BP1 Recombinant Antibody (clone 4G1C6) WB, IHC, ICC, FC, ELISA Mouse IgG1
    VS3-XY1543 Mouse Anti-TP53BP1 Recombinant Antibody (clone 8D5) ELISA, WB, IHC, FC Mouse IgG1

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