Recombinant Human Anti-VEEV E2 Antibody scFv Fragment (3B4C-4)

CAT#: PSBL-735

Recombinant Human Antibody (3B4C-4) scFv Fragment is specific to VEEV E2, expressed in E. coli. This scFv fragment abrogate VEEV infectivity by binding to the E2 (envelope) surface glycoprotein.

Specifications

  • Immunogen
  • VEEV E2 envelop protein
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • scFv
  • Specificity
  • Tested positive against native VEEV E2
  • Species Reactivity
  • VEEV
  • Clone
  • 3B4C-4
  • Applications
  • Can be useful in applications such as: Neutralization

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • E2 envelop protein; E2; envelop
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Breast cancer biomarkers at key points during disease progression
Applicable to multiple VEEV strains in vitro
We used the 3B4C-4 scFv fragment in our latest neutralization studies, and the results were impressive. It successfully neutralized multiple VEEV strains in vitro. Next step: testing in vivo. Great product so far!
Breast cancer biomarkers at key points during disease progression
Robust performance in competitive binding assays
We've used various scFv fragments before, but the 3B4C-4 stands out for its robust performance in competitive binding assays. It outperformed similar products on the market. Five stars from our team!
Breast cancer biomarkers at key points during disease progression
High specificity
Its performance in competitive binding assays was exceptional. The fragment maintains high specificity, making it ideal for applications requiring precise antigen detection. It's a highly dependable product.

Q&As

  1. Can this antibody fragment be used in vivo for therapeutic applications?

    A: While the 3B4C-4 scFv fragment has shown promising results in vitro, further preclinical animal studies are recommended to confirm its safety and efficacy in vivo before considering therapeutic applications in humans.

  2. Does the antibody fragment form aggregates, and what are the implications for its use?

    A: The 3B4C-4 scFv segment was designed to decrease aggregation. Aggregation may occur over time or under inadequate storage conditions. Aggregates have the potential to diminish efficacy and safety, highlighting the importance of correct storage and management.

  3. How does the antibody fragment perform in a competitive binding assay?

    A: The 3B4C-4 scFv fragment performs admirably in competitive binding experiments, retaining high specificity and affinity even in the presence of competing molecules, making it perfect for use in research.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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