Anti-VZV gH Recombinant Antibody (Hu206) (CAT#: MRO-1156LC)
This product is a recombinant humanized anti-Varicella-zoster virus monoclonal antibody. Hu206 specifically binds to gH glycoprotein associated with VZV and can be potentially used in the treatment and diagnosis of Varicella-zoster virus infection.
Specific Inquiry
ELISA
Figure 1 Antigen binding cell monolayer ELISA.
Parental hu206 MAb (▾) was compared to hu206 scAb-14 (•) binding to VZV infected cells. Binding of hu206 MAb (▿) and scAb-14 (○) to uninfected cells was also tested.
Multimeric humanized varicella-zoster virus antibody fragments to gH neutralize virus while monomeric fragments do not
Neut
Figure 2 Plaque reduction neutralization assay using antibodies and antibody fragments.
The samples tested were hu206 MAb (▴), hu206 scAb-14 (•), scAb-5 (▾), scAb-0 (▪), scAb-14 pre-incubated with secondary antibody (○) and secondary antibody alone (□). Each point represents a mean of three replicates, and each experiment was performed in duplicate.
Multimeric humanized varicella-zoster virus antibody fragments to gH neutralize virus while monomeric fragments do not
ELISA
Figure 3 Papain was used to digest whole hu206 antibody, and when tested for antigen binding in a cell monolayer ELISA.
Antigen binding cell monolayer ELISA of proteolytically generated hu206 Fab fragments and whole MAb hu206. The samples tested were hu206 Fab (▾) and MAb (•) binding to VZV infected monolayers, and hu206 Fab (▿) and MAb (○) binding to uninfected monolayers.
Multimeric humanized varicella-zoster virus antibody fragments to gH neutralize virus while monomeric fragments do not
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Varicella-zoster virus
- Clone
- Hu206
- Applications
- ELISA, Neut
- Related Disease
- Varicella-zoster virus infection
Applications
- Application Notes
- The VZV gH antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Neutralization.
Target
- Alternative Names
- Varicella-zoster virus; VZV; Varicella-zoster virus glycoprotein H; VZV gH
- Gene ID
- 1487668
- UniProt ID
- Q6YPA5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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See other products for "Clone Hu206"
See other products for "VZV gH"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2690CQ | Recombinant Mouse Anti-VZV gH Antibody (6A6) | IF | Mouse antibody |
| MRO-2700CQ | Recombinant Mouse Anti-VZV gH Antibody (9i77) | IP, WB | Mouse antibody |
| FAMAB-0726WJ | Mouse Anti-VZV gH Recombinant Antibody (clone RM-2D6) | ELISA, WB, Neut | Mouse IgG1, κ |
| FAMAB-0727WJ | Mouse Anti-VZV gH Recombinant Antibody (clone 302-1G9) | ELISA, WB, Neut | Mouse IgA1, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1155LC | Anti-VZV gH Recombinant Antibody (206) | ELISA, Neut, IHC, IF | Mouse Antibody |
| MRO-1155LC-S(P) | Anti-VZV gH Recombinant Antibody scFv Fragment (206) | ELISA | Mouse Antibody |
| MRO-1155LC-F(E) | Anti-VZV gH Recombinant Antibody Fab Fragment (206) | ELISA | Mouse Antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1156LC-S(P) | Anti-VZV gH Recombinant Antibody scFv Fragment (Hu206) | ELISA | Humanized antibody |
| MRO-1156LC-F(E) | Anti-VZV gH Recombinant Antibody Fab Fragment (Hu206) | ELISA | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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