Recombinant Human Anti-hMPV Antibody (NAb DS7)
CAT#: PABL-575
Recombinant Human Antibody (NAb DS7) is capable of binding to hMPV, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-hMPV mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-hMPV proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Published Data
Figure 1 SPR analysis of DS7 Fab.
(A) Association-dissociation curves of decreasing concentrations of DS7 against immobilized hMPV F△TM protein. Palivizumab (RSV F-specific MAb) was used as an irrelevant control. (B) Association-dissociation curves of DS7 at 100 nM against immobilized hMPV F△TM protein and RSV F TM protein.
In, F. P. T. N. V. (2007). A Recombinant Human Monoclonal. J. Virol, 81(15), 8315.
Figure 2 Immunofluorescent analysis of hMPV-infected LLC-MK2 cell monolayers with anti- hMPV F Fab DS7.
Light-microscopic and immunofluorescent images of hMPV-infected LLC-MK2 cell monolayers stained with human anti- hMPV F Fab and AlexaFluor568-conjugated goat anti-human IgG. (A and B) Fab ACN044; (C and D) Fab DS7. Magnification, 20.
In, F. P. T. N. V. (2007). A Recombinant Human Monoclonal. J. Virol, 81(15), 8315.
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Specifications
- Immunogen
- hMPV Human metapneumovirus
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native hMPV
- Species Reactivity
- hMPV
- Clone
- NAb DS7
- Applications
- IF Assay-depended
Neut Assay-depended
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- Human metapneumovirus; Hmpv
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
| MOB-505 | Recombinant Anti-hMPV Antibody | ELISA, IP, FuncS | IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-505-F(E) | Recombinant Anti-hMPV Antibody Fab Fragment | RIA, WB, FuncS | Fab |
| MHH-505-F(E) | Recombinant Human Anti-hMPV Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
| PFBL-570 | Recombinant Human Anti-hMPV Antibody Fab Fragment (NAb DS7) | Neut | Fab |
| HPAB-0102-WJ-F(E) | Human Anti-HMPV Recombinant Antibody; Fab Fragment (HPAB-0102-WJ-F(E)) | ELISA, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-505-S(P) | Recombinant Anti-hMPV Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| MHH-505-S(P) | Recombinant Human Anti-hMPV Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| PSBL-570 | Recombinant Human Anti-hMPV Antibody scFv Fragment (NAb DS7) | Neut | scFv |
| HPAB-0102-WJ-S(P) | Human Anti-HMPV Recombinant Antibody; scFv Fragment (HPAB-0102-WJ-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-106 | Recombinant Human Anti-HMPV Antibody (PABX-106) | ELISA, Neut, FuncS | IgG |
| PABX-106-F (E) | Recombinant Human Anti-HMPV Antibody Fab Fragment (PABX-106-F (E)) | ELISA, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-106-S (P) | Recombinant Human Anti-HMPV Antibody scFv Fragment (PABX-106-S (P)) | ELISA, Neut, FuncS | scFv |
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