BV421-A*02:01/Human NY-ESO-1 (SLLMWITQC) MHC Tetramer
CAT#: MHC-LC091
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of NY-ESO-1-derived peptide of SLLMWITQC sequence covering 157-165 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 Testis
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15453/34589_A_6_6.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B
❮
❯
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- NY-ESO-1
- Antigen Species
- Human
- Peptide
- SLLMWITQC
- Range
- 157-165
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence.
- Alternative Names
- CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1
- Gene ID
- 1485
- UniProt ID
- P78358
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MHC-LC091. Click the button above to contact us or submit your feedback about this product.
Robust Flow Cytometry Tool
The MHC tetramer's robust performance in flow cytometry elevates our analysis of antigen-specific T cells. Its bright fluorophore ensures high detection sensitivity, crucial for identifying rare T cell populations responding to tumor antigens.
Essential for Targeted Research
In our research on cancer/testis antigens, this tetramer serves as an essential tool for studying key immune responses. Its specificity for the NY-ESO-1 antigen aids in the precise targeting and assessment of T cell engagement in therapeutic scenarios.
Q&As
-
How does conjugation with BV421 enhance the functionality of this tetramer?
A: The BV421 fluorophore provides a bright and stable fluorescent signal, greatly enhancing the visibility and differentiation of antigen-specific T cells in flow cytometry, which is crucial for accurate T cell enumeration and phenotyping.
-
What makes this MHC tetramer useful in cancer immunology?
A: NY-ESO-1 is a cancer/testis antigen overexpressed in various tumors, making this tetramer pivotal for identifying and characterizing T cells that target tumor-specific antigens, aiding in the development of targeted immunotherapies.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CTAG1B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1275z | Mouse Anti-CTAG1B Recombinant Antibody (clone 8G5) | WB, ICC, IF, IHC | Mouse IgG1 |
| VS3-FY1582 | Mouse Anti-CTAG1B Recombinant Antibody (clone ZN72) | IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-193CL | Human Anti-CTAG1B Recombinant Antibody (TAB-193CL) | ELISA | Human IgG |
| TAB-608MZ | Human Anti-CTAG1B Recombinant Antibody (TAB-608MZ) | ELISA, IHC, FuncS | Human IgG1 |
| TAB-608MZ-S(P) | Human Anti-CTAG1B Recombinant Antibody; scFv Fragment (TAB-608MZ-S(P)) | ELISA, IHC | Human scFv |
| TAB-608MZ-F(E) | Human Anti-CTAG1B Recombinant Antibody; Fab Fragment (TAB-608MZ-F(E)) | ELISA, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0850 | Hi-Affi™ Rabbit Anti-CTAG1B Recombinant Antibody (clone DS850AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1746 | Anti-CTAG1B Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
-2.png)
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
-4.jpg)
Application: FC, FuncS, IA, IF, IP, IHC
Application: ELISA, Block, WB, FC, IP
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
