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    PE-A*02:01/Human NY-ESO-1 (SLLMWITQC) MHC Tetramer (CAT#: MHC-LC109)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of NY-ESO-1-derived peptide of SLLMWITQC sequence covering 157-165 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Testis
    Figure 1 Testis
    (Pachytene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Preleptotene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Round or early spermatids
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15453/34589_A_6_6.jpg
    RNA Expression
    Figure 2 RNA cell line category: Cell line enriched (U-266/70)
    Figure 2 RNA cell line category: Cell line enriched (U-266/70)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B
    Figure 2 RNA cell line category: Cell line enriched (U-266/70)
    Figure 2 RNA cell line category: Cell line enriched (U-266/70)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B

    Specifications

    • Allele
    • A*02:01
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • NY-ESO-1
    • Antigen Species
    • Human
    • Peptide
    • SLLMWITQC
    • Range
    • 157-165
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence.
    • Alternative Names
    • CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1

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