Recombinant Anti-CD22 × Anti-CD19 Bispecific Antibody (Tandem Diabody) (CAT#: TAND-L038)
Recombinant Anti-CD22 × Anti-CD19 Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to one cell surface antigens and the other two to the other cells. Tandem Diabodies do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs but larger than tandem scFvs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with tandem scFvs. It was designed for the treatment of breast cancer, non-Hodgkin's lymphoma (NHL), acute myeloid leukemia (AML).
Specific Inquiry
Specifications
- Target
- CD22 & CD19
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- CD22
- Host Species 1
- Human
- Target 2
- CD19
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Breast cancer, Non-Hodgkin's lymphoma (NHL), Acute myeloid leukemia (AML)
Target
- Target 1
- CD22
- Gene ID
- 933
- UniProt ID
- P20273
- Alternative Names
- CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
- Target 2
- CD19
- Gene ID
- 930
- UniProt ID
- P15391
- Alternative Names
- CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAND-L038. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, Neut, FuncS
Application: ELISA, SPR, Inhib, FuncS
-3.png)
Application: ELISA, FC, Block, SPR
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: FC
Application: ELISA, FC, WB, Inhib, IHC
Application: Neut, FuncS, IHC, ELISA, FC, Inhib
Application: ELISA, FC, FuncS
Application: ELISA, Inhib, FuncS
Application: WB, IHC-Fr, IHC-P, ICC, IF
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
