This immunotoxin was achieved by conjugating/fusing the CD4 to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to cells infected with HIV. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of AIDS.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-466 | Recombinant Anti-HIV Antibody | WB, FC, FuncS | IgG |
MHH-466 | Recombinant Human Anti-HIV Antibody | RIA, ELISA, FuncS | IgG |
PABL-136 | Mouse Anti-HIV Recombinant Antibody (clone YZ23) | WB, ELISA, FuncS | Mouse IgG |
PABL-383 | Mouse Anti-HIV Recombinant Antibody (clone YZ18) | WB, Neut, FuncS | Mouse IgG |
HPAB-1194LY | Human Anti-HIV Recombinant Antibody (HPAB-1194LY) | Neut, ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-466-S(P) | Recombinant Anti-HIV Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
MHH-466-S(P) | Recombinant Human Anti-HIV Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
HPAB-1194LY-S(P) | Human Anti-HIV Recombinant Antibody; scFv Fragment (HPAB-1194LY-S(P)) | Neut, ELISA | Human scFv |
HPAB-0182-WJ-S(P) | Human Anti-HIV Recombinant Antibody; scFv Fragment (HPAB-0182-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-0825-FY-F(E) | Human Anti-HIV Recombinant Antibody; Fab Fragment (HPAB-0825-FY-F(E)) | Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L021G | CD4-Gel immunotoxin | Cytotoxicity assay, Functional assay | |
AGTO-L059G | anti-HIV immunotoxin G49 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L059R | anti-HIV immunotoxin G49 (IgG)-RTA | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2936LY-F(E) | Human Anti-HIV Recombinant Antibody; Fab Fragment (HPAB-2936LY-F(E)) | ELISA | Humanized Fab |
HPAB-2937LY-F(E) | Human Anti-HIV Recombinant Antibody; Fab Fragment (HPAB-2937LY-F(E)) | ELISA | Humanized Fab |
HPAB-2938LY-F(E) | Human Anti-HIV Recombinant Antibody; Fab Fragment (HPAB-2938LY-F(E)) | ELISA | Humanized Fab |
HPAB-2939LY-F(E) | Human Anti-HIV Recombinant Antibody; Fab Fragment (HPAB-2939LY-F(E)) | ELISA | Humanized Fab |
HPAB-2940LY-F(E) | Human Anti-HIV Recombinant Antibody; Fab Fragment (HPAB-2940LY-F(E)) | ELISA | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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