H-2Kb/HSV-1 glycoprotein B (SSIEFARL) MHC Tetramer
CAT#: MHC-LC537
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HSV-1-derived peptide of SSIEFARL sequence covering 498-505 and H-2Kb molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Kb
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- HSV-1 glycoprotein B
- Antigen Species
- HSV-1
- Peptide
- SSIEFARL
- Range
- 498-505
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus.
- Alternative Names
- HSV-1 gB; Human herpesvirus 1 envelope glycoprotein B
- Gene ID
- 24271469
- UniProt ID
- P10211
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Q&As
-
What is the primary research application of the H-2Kb/HSV-1 gB MHC Tetramer?
A: This tetramer is mainly used for identifying and analyzing CD8 T cells specific to the HSV-1 glycoprotein B antigen in mouse models, utilizing flow cytometry techniques to study immune responses against HSV-1.
-
Can this tetramer be used for in vivo imaging studies?
A: While its primary application is for flow cytometry, modifications and conjugation with suitable imaging agents could potentially allow for use in tracking immune responses in vivo.
View the frequently asked questions answered by Creative Biolabs Support.
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