H-2Kb/HSV-1 glycoprotein B (SSIEFARL) MHC Tetramer

CAT#: MHC-LC537

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HSV-1-derived peptide of SSIEFARL sequence covering 498-505 and H-2Kb molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • H-2Kb
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • HSV-1 glycoprotein B
  • Antigen Species
  • HSV-1
  • Peptide
  • SSIEFARL
  • Range
  • 498-505
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus.
  • Alternative Names
  • HSV-1 gB; Human herpesvirus 1 envelope glycoprotein B
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Breast cancer biomarkers at key points during disease progression
Optimal for Mouse Models
Designed for mouse models, it integrates easily into our research protocols. Its compatibility ensures consistent and meaningful results, furthering our investigations into HSV-1 immunodynamics.
Breast cancer biomarkers at key points during disease progression
Stable and Accurate Results
Stability and accuracy are hallmark benefits of this product. Its reliable performance translates into robust data, pivotal for our immunological research, especially when dissecting the impacts of HSV-1 on immune functions.

Q&As

  1. What is the primary research application of the H-2Kb/HSV-1 gB MHC Tetramer?

    A: This tetramer is mainly used for identifying and analyzing CD8 T cells specific to the HSV-1 glycoprotein B antigen in mouse models, utilizing flow cytometry techniques to study immune responses against HSV-1.

  2. Can this tetramer be used for in vivo imaging studies?

    A: While its primary application is for flow cytometry, modifications and conjugation with suitable imaging agents could potentially allow for use in tracking immune responses in vivo.

View the frequently asked questions answered by Creative Biolabs Support.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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