Ibritumomab tiuxetan
CAT#: TP-106CL
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.
Specifications
- Type
- Biotech
- Trade name
- Zevalin
- UNII
- 4Q52C550XK
Target
- Function
- A mAb portion that recognizes CD20+ B cells and induces apoptosis while the chelation site allows either imaging (In-111) or cellular damage by beta emission (Y-90)
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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