Ibritumomab tiuxetan
CAT#: TP-106CL
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.
Specifications
- Type
- Biotech
- Trade name
- Zevalin
- UNII
- 4Q52C550XK
Target
- Function
- A mAb portion that recognizes CD20+ B cells and induces apoptosis while the chelation site allows either imaging (In-111) or cellular damage by beta emission (Y-90)
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for TP-106CL. Click the button above to contact us or submit your feedback about this product.
High Specificity For CD20 Antigen
Our lab utilized this Indium or yttrium conjugated murine antibody to target the CD20 antigen on B lymphocytes. The specificity for the CD20+ B cells was impressive, and the conjugation facilitated our imaging protocols effectively. The recombinant production in CHO cells seems to ensure high quality.
Excellent Conjugated Monoclonal Antibody
We were looking for a murine IgG1 kappa monoclonal antibody that interacts with the CD20 antigen for our cellular studies. This Ibritumomab tiuxetan product performed exactly as described. The chelation site's capability for isotope conjugation was a key feature that supported our experimental design involving cellular interaction analysis.
Q&As
-
What is the composition and host source of this antibody?
A: This is an Indium or yttrium conjugated murine monoclonal antibody. It is produced in Chinese hamster ovary (CHO) cells and is composed of two murine gamma 1 heavy chains and two kappa light chains.
-
What is the specific target of this antibody?
A: The antibody is directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. It is designed to recognize CD20+ B cells and can induce apoptosis or be used for imaging via its chelation site.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, Cyt, Stim, PP, Agonist
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, WB, BLI, SPR
Application: ELISA, PD, Activ, PK, Stim
Application: ELISA, WB, IF, FC, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
