PE-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer
CAT#: MHC-LC671
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of IAPP-derived peptide of KLQVFLIVL sequence covering 5-13 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
Normal Tissue
Figure 2 High expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 Low expression in colon
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
Normal Tissue
Figure 4 Pancreas
Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- IAPP
- Antigen Species
- Human
- Peptide
- KLQVFLIVL
- Range
- 5-13
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.
- Alternative Names
- IAPP; islet amyloid polypeptide; DAP; IAP
- Gene ID
- 3375
- UniProt ID
- P10997
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Datasheet
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COA
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See other products for "IAPP"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2254z | Mouse Anti-IAPP Recombinant Antibody (clone 35D9) | ICC, IF, IHC | Mouse IgG1 |
| HPAB-0295-YC | Human Anti-IAPP Recombinant Antibody (clone HlLl) | FuncS | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-375CL | Human Anti-IAPP Recombinant Antibody (TAB-375CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CT | Human Anti-IAPP Recombinant Antibody (TAB-118CT) | ELISA | Human IgG |
| TAB-119CT | Human Anti-IAPP Recombinant Antibody (TAB-119CT) | ELISA | Human IgG |
| TAB-120CT | Human Anti-IAPP Recombinant Antibody (TAB-120CT) | ELISA | Human IgG |
| TAB-118CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-118CT-S(P)) | ELISA | Human scFv |
| TAB-119CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-119CT-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC672 | APC-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC673 | BV421-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-YF299 | A*02:01/Human IAPP (KLQVFLIVL) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-S(P) | Human Anti-IAPP Recombinant Antibody (clone HlLl); scFv Fragment | FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-F(E) | Human Anti-IAPP Recombinant Antibody (clone HlLl); Fab Fragment | FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3366 | Anti-IAPP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC148 | Recombinant Anti-IAPP Eliminating Antibody, pH-Sensitive (VS-0625-YC148) | Antigen-Sweeping In Vivo. | Human IgG |
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