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IAPP
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- Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-119CT-F(E)) (TAB-119CT-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody (TAB-375CL) (TAB-375CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Mouse Anti-IAPP Recombinant Soluble TCR (BDC-5.2.9) (scTCR-267ZP-S(P))
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- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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- A*02:01/Human IAPP (KLQVFLIVL) MHC Monomer (MHC-YF299)
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- Class: Class I
- Antigen: IAPP
- Antigen Species: Human
- Peptide: KLQVFLIVL
- Conjugate: Biotin
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- Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (C-Cys) (VS-0622-YF3730)
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- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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- Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (KIH) (VS-0622-YF6438)
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- Species Reactivity: Mouse
- Epitope: KCNTATCATQRLANFLVRSS
- MHC: HLA class II
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- PE-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer (MHC-LC671)
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- Class: Class I
- Antigen: IAPP
- Antigen Species: Human
- Peptide: KLQVFLIVL
- Conjugate: PE
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- APC-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer (MHC-LC672)
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- Class: Class I
- Antigen: IAPP
- Antigen Species: Human
- Peptide: KLQVFLIVL
- Conjugate: APC
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- Human Anti-IAPP Recombinant Antibody (clone HlLl) (HPAB-0295-YC)
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- Derivation: Humanized
- Species Reactivity: Human, Rat
- Type: Humanized IgG1, κ
- Application: FuncS
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- Human Anti-IAPP Recombinant Antibody (clone HlLl); scFv Fragment (HPAB-0295-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Rat
- Type: Humanized scFv
- Application: FuncS
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- Human Anti-IAPP Recombinant Antibody (clone HlLl); Fab Fragment (HPAB-0295-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Rat
- Type: Humanized Fab
- Application: FuncS
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- Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-118CT-S(P)) (TAB-118CT-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-119CT-S(P)) (TAB-119CT-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-120CT-S(P)) (TAB-120CT-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-118CT-F(E)) (TAB-118CT-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody (TAB-118CT) (TAB-118CT)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody (TAB-119CT) (TAB-119CT)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody (TAB-120CT) (TAB-120CT)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-120CT-F(E)) (TAB-120CT-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Anti-IAPP Immunohistochemistry Kit (VS-0525-XY3366)
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- Species Reactivity: Human
- Target: IAPP
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimers disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity.
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Early spermatids, Pancreatic endocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (U-2 OS)
Interaction
Interacts with IDE and INS. Can form homodimers. Interaction with INS inhibits homodimerization and fibril formation.
Molecular function
Hormone
More Types Infomation