PE-A*29:02/Human PSMA3 (YMIDPSGVSY) MHC Tetramer
CAT#: MHC-LC4319
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PSMA3 of peptide YMIDPSGVSY covering 150-159 and A*29:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- A*29:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- PSMA3
- Antigen Species
- Human
- Peptide
- YMIDPSGVSY
- Range
- 150-159
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Alternative Names
- PSMA3; Proteasome subunit alpha type-3; HC8; PSC3
- Gene ID
- 5684
- UniProt ID
- P25788
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