PE-B*58:01/Human PSMA3 (YMIDPSGVSY) MHC Tetramer (CAT#: MHC-LC4320)

• Allele
• B*58:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• PSMA3

• Antigen Species
• Human

• Peptide
• YMIDPSGVSY

• Range
• 150-159

• Conjugate
• PE

• Application
• FCM

• Antigen Introduction
• The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Alternative Names
• PSMA3; Proteasome subunit alpha type-3; HC8; PSC3

• Gene ID
• 5684

• UniProt ID
• P25788

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