PE-A*68:02/Human MYH9 (ELTCLNEASV) MHC Tetramer

CAT#: MHC-LC3931

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human MYH9 of peptide ELTCLNEASV covering 88-97 and A*68:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line U-251 MG Figure 2 IF staining of human cell line A-431 Figure 3 IF staining of human cell line U-2 OS Figure 4 Cerebral cortex Figure 5 Colon Figure 6 Kidney Figure 7 Testis Figure 8 Endometrium Figure 9 Lymph node Figure 10 RNA cell line category: Cell line enhanced (TIME)

Specifications

  • Allele
  • A*68:02
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • MYH9
  • Antigen Species
  • Human
  • Peptide
  • ELTCLNEASV
  • Range
  • 88-97
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
  • Alternative Names
  • MYH9; Myosin-9; MHA; FTNS; EPSTS; BDPLT6; DFNA17; NMMHCA; NMHC-II-A; NMMHC-IIA
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