PE-Gogo-B*0101/Human FDPS (KRYKSIVKY) MHC Tetramer
CAT#: MHC-LC3040
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human FDPS of peptide KRYKSIVKY covering 191-199 and Gogo-B*0101 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_B_7_5.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HBEC3-KT)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160752-FDPS
❮
❯
Specifications
- Allele
- Gogo-B*0101
- Class
- Class I
- MHC Species
- Gorilla
- Antigen
- FDPS
- Antigen Species
- Human
- Peptide
- KRYKSIVKY
- Range
- 191-199
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
- Alternative Names
- FDPS; Farnesyl pyrophosphate synthetase; FPS; FPPS; POROK9
- Gene ID
- 2224
- UniProt ID
- P14324
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "FDPS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1279 | Hi-Affi™ Rabbit Anti-FDPS Recombinant Antibody (clone DS1279AB) | FC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-295YJL | Rabbit Anti-FDPS Recombinant Antibody (clone CBF278) | ELISA | Rabbit IgG |
| MOB-299YJL | Rabbit Anti-FDPS Recombinant Antibody (clone CBF282) | ELISA | Rabbit IgG |
| VS3-FY1716 | Rabbit Anti-FDPS Recombinant Antibody (clone R07-2G6) | WB, IHC-P | Rabbit IgG |
| VS3-FY2703 | Mouse Anti-FDPS Recombinant Antibody (VS3-FY2703) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC766 | AbPlus™ Anti-Fdps Magnetic Beads (VS-0724-YC766) | IP, Protein Purification | |
| VS-0724-YC767 | AbPlus™ Anti-FDPS Magnetic Beads (VS-0724-YC767) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2495 | Anti-FDPS Immunohistochemistry Kit | IHC |
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