Rabbit Anti-FDPS Recombinant Antibody (clone R07-2G6)
CAT#: VS3-FY1716
The R07-2G6 recombinant monoclonal antibody recognize human FDPS. It cross-reacts with hamster. It is suitable for use in a variety of assays, including WB, IHC-P. This FDPS antibody has been rigorously validated and is widely used in western blot analysis of FDPS in CHO-K1 lysates.
Gene Expression
Tested Data
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_B_7_5.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28200/59804_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HBEC3-KT)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160752-FDPS
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WB
Figure 1 Anti-FDPS Antibody (VS3-FY1716) in WB.
The FDPS expression in CHO-K1 lysates were detected using the anti-FDPS by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human FDPS
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Hamster FDPS
- Species Reactivity
- Human, Hamster
- Clone
- R07-2G6
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 48 kDa, while the observed molecular weight stands at 48 kDa.
- Related Disease
- Diseases related to bone resorption
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Farnesyl Diphosphate Synthase; Farnesyl Pyrophosphate Synthetase, Dimethylallyltranstransferase, Geranyltranstransferase; (2E,6E)-Farnesyl Diphosphate Synthase; FPP Synthase; FPS; Farnesyl Pyrophosphate Synthase; Dimethylallyltranstransferase; Geranyltranstransferase
- Gene ID
- 2224
- UniProt ID
- P14324
- Sequence Similarities
- Belongs to the FPP/GGPP synthase family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Acetylation
Hydroxylation
- Protein Refseq
- NP_001129293.1; NP_001129294.1; NP_001229753.1; NP_001229754.1; NP_001365353.1
- Function
- Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "FDPS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1279 | Hi-Affi™ Rabbit Anti-FDPS Recombinant Antibody (clone DS1279AB) | FC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3040 | PE-Gogo-B*0101/Human FDPS (KRYKSIVKY) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-295YJL | Rabbit Anti-FDPS Recombinant Antibody (clone CBF278) | ELISA | Rabbit IgG |
| MOB-299YJL | Rabbit Anti-FDPS Recombinant Antibody (clone CBF282) | ELISA | Rabbit IgG |
| VS3-FY2703 | Mouse Anti-FDPS Recombinant Antibody (VS3-FY2703) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC766 | AbPlus™ Anti-Fdps Magnetic Beads (VS-0724-YC766) | IP, Protein Purification | |
| VS-0724-YC767 | AbPlus™ Anti-FDPS Magnetic Beads (VS-0724-YC767) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2495 | Anti-FDPS Immunohistochemistry Kit | IHC |
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