AbPlus™ Anti-FDPS Magnetic Beads (VS-0724-YC767) (CAT#: VS-0724-YC767)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-FDPS specific antibody

• Target
• FDPS

• Immunogen
• Recombinant human FDPS/Farnesyl Diphosphate Synthase, aa 1-353.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]

• Alternative Names
• Farnesyl Diphosphate Synthase; Farnesyl Pyrophosphate Synthetase, Dimethylallyltranstransferase, Geranyltranstransferase; (2E,6E)-Farnesyl Diphosphate Synthase; FPP Synthase; FPS; Farnesyl Pyrophosphate Synthase; Dimethylallyltranstransferase; Geranyltranstransferase;

• Gene ID
• 2224

• UniProt ID
• P14324

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