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PE-Gogo-B*0101/Human HIST3H3 (RRYQKSTEL) MHC Tetramer (CAT#: MHC-LC3042)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HIST3H3 of peptide RRYQKSTEL covering 53-61 and Gogo-B*0101 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/if_selected.jpg
Normal Tissue
Figure 2 Lymph node
Figure 2 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_A_8_8.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_B_9_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_A_9_3.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_A_8_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_A_4_6.jpg
Figure 8 Skin
Figure 8 Skin
(Fibroblasts Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Keratinocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Langerhans Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3812/10149_B_7_1.jpg

Specifications

  • Allele
  • Gogo-B*0101
  • Class
  • Class I
  • Antigen
  • HIST3H3
  • Antigen Species
  • Human
  • Peptide
  • RRYQKSTEL
  • Range
  • 53-61
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
  • Alternative Names
  • HIST3H3; Histone H3.1t; H3t; H3.4; H3/g; H3FT

Downloads

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See other products for "HIST3H3"

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1611 Rabbit Anti-HIST3H3 Recombinant Antibody (clone DS1611AB) WB, IP, IHC Rabbit IgG
MOR-0034-FY Rabbit Anti-HIST3H3 Recombinant Antibody (clone AFY0005) ICC, IHC, WB, Inhib Rabbit IgG
MOR-0041-FY Rabbit Anti-HIST3H3 Recombinant Antibody (clone AFY0012) ICC, IHC-P, WB, Inhib Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC3389 PE-B27/Human HIST3H3 (RRYQKSTEL) MHC Tetramer FCM

Recombinant Antibody

CAT Product Name Application Type
HPAB-1984-FY Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis16) ELISA Human IgG
HPAB-1985-FY Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis18) ELISA Human IgG
HPAB-1986-FY Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis19) ELISA Human IgG
VS3-WK1018 Mouse Anti-HIST3H3 Recombinant Antibody (VS3-WK1018) WB, IHC, IF, IP, CHIP Mouse IgG
VS3-WK1019 Rabbit Anti-HIST3H3 Recombinant Antibody (VS3-WK1019) WB, IHC, ICC, IP Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-1984-FY-F(E) Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis16); Fab Fragment ELISA Human Fab
HPAB-1985-FY-F(E) Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis18); Fab Fragment ELISA Human Fab
HPAB-1986-FY-F(E) Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis19); Fab Fragment ELISA Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-1984-FY-S(P) Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis16); scFv Fragment ELISA Human scFv
HPAB-1985-FY-S(P) Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis18); scFv Fragment ELISA Human scFv
HPAB-1986-FY-S(P) Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis19); scFv Fragment ELISA Human scFv

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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