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HIST3H3
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- PE-B27/Human HIST3H3 (RRYQKSTEL) MHC Tetramer (MHC-LC3389)
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- Class: Class I
- Antigen: HIST3H3
- Antigen Species: Human
- Peptide: RRYQKSTEL
- Conjugate: PE
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis16) (HPAB-1984-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Mouse Anti-HIST3H3 Recombinant Antibody (VS3-WK1018) (VS3-WK1018)
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC, IF, IP, CHIP
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, ICC, IP
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- Human Anti-HIST3H3 Antibody (clone SLEhis16), mRNA (HPAB-1984-FY-mRNA)
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- Species Reactivity: Human
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- Human Anti-HIST3H3 Antibody (clone SLEhis18), mRNA (HPAB-1985-FY-mRNA)
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- Species Reactivity: Human
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- Human Anti-HIST3H3 Antibody (clone SLEhis19), mRNA (HPAB-1986-FY-mRNA)
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- Species Reactivity: Human
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis18) (HPAB-1985-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis19) (HPAB-1986-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis19); Fab Fragment (HPAB-1986-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis19); scFv Fragment (HPAB-1986-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis18); Fab Fragment (HPAB-1985-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis18); scFv Fragment (HPAB-1985-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis16); Fab Fragment (HPAB-1984-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-HIST3H3 Recombinant Antibody (clone SLEhis16); scFv Fragment (HPAB-1984-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Rabbit Anti-HIST3H3 Recombinant Antibody (clone AFY0005) (MOR-0034-FY)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: ICC, IHC, WB, Inhib
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- Rabbit Anti-HIST3H3 Recombinant Antibody (clone AFY0012) (MOR-0041-FY)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB, Inhib
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More Infomation
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For Research Use Only. Not For Clinical Use.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Predicted location
Intracellular
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with TONSL; CHAF1A and CHAF1B (PubMed:33857403).
Molecular function
DNA-binding
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