PE-H-2Kb/OVA (SIIGFEKL) MHC Tetramer

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Q&As

1. What is the primary application of the PE-H-2Kb/OVA MHC Tetramer?

   A: The PE-H-2Kb/OVA MHC Tetramer is primarily used in flow cytometry to analyze antigen-specific CD8+ T cells in mouse models. Researchers utilize this tool to measure immune responses, particularly in studies involving ovalbumin as a model antigen.

2. What are the typical research areas where this tetramer is used?

   A: The PE-H-2Kb/OVA MHC Tetramer is often used in immunology studies, including cancer research, vaccine development, and autoimmune disease exploration, among others. Its applications are broad, given its role in tracking T cell responses.

3. What controls should I consider using with this tetramer in assays?

   A: Appropriate controls include staining with a non-specific tetramer or using cells known to lack the T cell receptor specificity for SIIGFEKL. Isotype controls and unstained cells are also recommended for accurate analysis.

View the frequently asked questions answered by Creative Biolabs Support.

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