PE-I-Ab/OVA (ISQAVHAAHAEINEAGR) MHC Tetramer (CAT#: MHC-LC657)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of OVA-derived peptide of ISQAVHAAHAEINEAGR sequence covering 323-339 and I-Ab molecule. The pMHC tetramer recognizes mouse CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- I-Ab
- Class
- Class II
- MHC Species
- Mouse
- Antigen
- OVA
- Antigen Species
- Gallus gallus
- Peptide
- ISQAVHAAHAEINEAGR
- Range
- 323-339
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein.
- Alternative Names
- OVA; Ovalbumin
- Gene ID
- 396058
- UniProt ID
- P01012
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC648 | BV421-H-2Kb/OVA (SIINFEKL) MHC Tetramer | FCM | |
| MHC-LC649 | PE-H-2Kb/OVA (SIINFEKL) MHC Tetramer | FCM | |
| MHC-LC650 | APC-H-2Kb/OVA (SIINFEKL) MHC Tetramer | FCM | |
| MHC-LC651 | PE-H-2Kb/OVA (EIINFEKL) MHC Tetramer | FCM | |
| MHC-LC652 | APC-H-2Kb/OVA (EIINFEKL) MHC Tetramer | FCM |
Customer Reviews and Q&As
Customer Review
Q&As
Excellent for T Cell Analysis
Having used the PE-I-Ab/OVA MHC Tetramer, I found it an invaluable tool for precise detection and analysis of antigen-specific T cells. The fluorescent PE labeling made flow cytometry seamless and informative, greatly enhancing our understanding of immune cell dynamics in our research on autoimmune pathways.
Enhanced Sensitivity and Detection
The enhanced sensitivity offered by this tetramer over traditional methods was clear in our experiments. It helped capture low-frequency antigen-specific T cells, a crucial factor for our cancer immunology research, better guiding our therapeutic strategies.
Supports Aging Study Research
Ideal for characterizing how aging affects antigen-specific T cell responses-critical in our investigation of differential immune responses in older populations.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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